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Medical Book from C.H.I.P.S.

Amyotrophic Lateral Sclerosis
edited by Hiroshi Mitsumoto

Amyotrophic Lateral Sclerosis covers all the essential information clinicians require for daily practice, as well as providing a reader-friendly approach to every aspect of ALS.

Features:

  • Stands at the forefront of ALS neurobiology and research-addressing topics such as protein aggregation, excitotoxicity, apoptosis, genetic influence, and inflammation
  • Addresses translational research and high-throughput drug development
  • Discusses methods and techniques to maximize the quality of patient care and treatment
  • Fully details intensive pharmacotherapy for symptomatic management, as well as pharmacotherapy in clinical trials
  • Illustrates patient evaluation, diagnosis, and therapy, and outlines alternative treatment options
  • Assesses the strengths and limitations of individual ALS multidisciplinary team clinics approaches
  • Covers key issues in nutritional, respiratory, and end-of-life care
  • Reviews the history and epidemiology of the disease

Contents

  • Overview of Clinical ALS
  • History
  • Epidemiology
  • Pathology
  • Clinical Features: Motor System
  • Clinical Features: Dementia and Cognitive Deficits
  • Familial ALS and Genetic Approaches to ALS
  • Electrophysiology and Other Objective Markers
  • Classification, Diagnosis and Presentation of Diagnosis of ALS
  • Natural History
  • Translational Research in ALS: Mechanisms behind therapy
  • Motor Neuron: The origin, definition and function
  • Neurodegeneration
  • Excitotoxicity
  • Oxidative Stress. Neuroinflammation
  • Apoptosis
  • Cytoskeleton
  • Mitochondria
  • Environmental Neurotoxicity
  • Genetic Causes and Predisposition
  • Protein Aggregate Disease
  • Proteiomic and Metabolomic Approach
  • Infections and Autoimmunity
  • Gene Transfer Technology
  • High Through-put Technology
  • Animal Models
  • Restoration-Practical Approach
  • Clinical Trial Methodology
  • ALS Therapy: Care and Management
  • Multidisciplinary Approach: Ideal Care Centers and World Perspective
  • Impact of National ALS Care Database and Practice Parameters
  • Symptomatic Pharmacotherapy: Bulbar and Constitutional Symptoms
  • Pharmacotherapy: In clinical trials
  • Physical Rehabilitation
  • Speech Therapy and Augmentative Communication/Assistive Technology
  • Nutritional treatment: Theoretical and Practical issues
  • Respiratory care: Basic and Practical
  • Psychosocial care: Patient and Caregiver Support
  • Palliative Care
  • Palliative Care: Family Perspective
  • Decision Making for End of Life
  • National ALS Study Group: Future of ALS Clinical Research

Index

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Amyotrophic Lateral Sclerosis
edited by Hiroshi Mitsumoto
2005 864 pages $248.95 + shipping
Texas residents please add 6.75 % sales tax

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