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Laboratory Dermatology Testing Reference
from C.H.I.P.S.

Animal Models of Human Inflammatory Skin Diseases
edited by Lawrence S. Chan

Features:

  • Contains comprehensive information on a variety of animal models of inflammatory skin diseases
  • Provides theoretical guidance in experimental animal modeling
  • Supplies technical instruction in the induction and assessment of experimental animal models of inflammatory skin diseases
  • Includes a chapter on comparative histology and immunology
  • Presents information for potential targets of immunological intervention

Animal Models of Human Inflammatory Skin Diseases features the principles and practices of how to go about studying inflammatory skin diseases using live animal models. On the principle side, the book describes the comparative structure and function of the skin, and the comparative immunology system in animal species commonly used as models.

From the practical perspective, it presents a general discussion on methods of experimental animal modeling and contains specific expert experience on individual models. The authors include a detailed method of disease induction for each model, present chapters on comparative histology and immunology, and discuss potential targets of disease intervention.

Written by biomedical investigators with first-hand experience in their chosen fields, this book is a valuable guide and reference for investigators in the biomedical and pharmaceutical sciences.

It provides an instantaneous comparison between the skin structure and immunology of humans and animals, aiding in the interpretation and application of pathologic and immunologic findings.

Contents

  1. Comparative Structure and Function of the Skin
    • Comparative Structure and Function of the Skin: Overview of Structures and Components
    • Comparative Structure and Function of the Skin: Epithelial Basement Membrane Zone

  2. Comparative Immunology
    • Human Immune System
    • Canine Immune System
    • Rat Immune System
    • Mouse Immune System

  3. Immune Privilege and Skin Inflammation
    • Immune Privilege of the Eye
    • Theory of Immune Privilege of the Hair Follicle

  4. Methods of Experimental Animal Modeling
    • Passive Transfer and Active Induction of Autoimmune Diseases
    • Adoptive Transfer of Cellular Immunity
    • Molecular Biological Manipulation of the Immune System by Transgenic Techniques

  5. Inflammatory Skin Disease Models
    • Bullous Pemphigoid
    • Epidermolysis Bullosa Acquisita
    • Mucous Membrane Pemphigoid
    • Pemphigus Vulgaris
    • Pemphigus Foliaceus
    • Psoriasis
    • Atopic Dermatitis
    • Alopecia Areata
    • Scleroderma

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    Animal Models of Human
    Inflammatory Skin Diseases

    edited by Lawrence S. Chan
    584 pages $248.95 + shipping
    Texas residents please add 6.75 % sales tax

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