Antiplatelet Therapy in Ischemic Heart Disease explores and explains state-of-the-art use of antiplatelet agents and draws on the expertise of global leaders in antiplatelet therapy.

Skillfully organized for fast reference, Antiplatelet Therapy in Ischemic Heart Disease is divided into five parts:

• Concepts in Platelet Physiology, Function, and Measurement
• Pharmacology of Oral Antiplatelet Agents
• Pharmacology of Intravenous Antiplatelet Agents
• Clinical Use of Antiplatelet Agents in Cardiovascular Disease
• Special Circumstances

Each chapter in the clinical section contains an overview of guidelines, plus specifics on medical and interventional uses.

Clinical cardiologists, platelet biologists, and a wide range of practicing and prospective clinicians in allied fields will find this text an exceptional source of current information.

Contents

Concepts in Platelet Physiology, Function, and Measurement

1. Platelet physiology and the role of the platelet in ischemic heart disease
2. Laboratory assessment of platelet function and the effects of antiplatelet agents

Pharmaology of Oral Antiplatelet Agents

3. Cyclooxygenase inhibitors
4. Aspirin response variability and resistance
5. P2Y₁₂inhibitors: Thienopyridines and direct oral inhibitors
6. Thienopyridine response variability and resistance

Pharmacology of Intravenous Antiplatelet Agents

7. Pharmacology of intravenous glycoprotein IIb/IIIa antigonists
8. Intravenous P2Y₁₂inhibitiors
9. Antiplatelet effects of thrombin inhibitors and fibrinolytic agents

Clinical Use of Antiplatelet Agents in Cardiovascular Disease

10. Antiplatelet therapy in acute coronary syndrome without ST elevation
11. Antiplatelet therapy in ST-elevation myocardial infarction
12. Antiplatelet therapy in chronic coronary artery disease
13. Antiplatelet therapy in peripheral arterial disease
14. Clinical use of antiplatelet agents in cardiovascular disease: cerebrovascular diseases

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