Cellular Outcomes of Cancer Therapy
edited by Igor B. Roninson
Beyond Apoptosis provides an overview of how different biological mechanisms of cell death, senescence and mitotic catastrophe stop the growth of tumor cells treated with anticancer agents.
Beyond Apoptosis's goal is to examine the relative contribution of apoptosis, and to acquaint the readers with new concepts in non-apoptotic cell death, senescence, and mitotic catastrophe.
- A Personal History of the Development of the Apoptosis Concept
- What do the Clinical Data Tell Us About the Role of Apoptosis in Sensitivity to Cancer Therapy?
- Response of Solid Tumors to Cancer Therapy: How Relevant is Apoptosis?
- Historical Studies of Various Forms of Cell Death
- Toward a Mechanistic Taxonomy for Programmed Cell Death Pathways
- Caspase-Independent Apoptotic Cell Death
- Autophagic Cell Death in Mammalian Cells
- The Cellular Decision Between Apoptosis and Autophagy
- Parthanatos: PARP- and AIF-Dependent Programmed Cell Death
- Cellular Senescence and Its Effects on Carcinogenesis
- Tumor Suppressing Activities of Senescent Keratinocytes
- Senescence Induced by Repression of Human Papillomavirus Oncogenes in Cervical Cancer Cells
- Treatment-Induced Tumor Cell Senescence and Its Consequences
- Senescence Regulation in Cancer Therapy
- Exploiting Drug-Induced Senescence in Transgenic Mouse Models
- Therapy-Induced Cellular Senescence: Clinical Relevance, Implications, and Applications
- Mitotic Catastrophe in Cancer Therapy
- How Do Cells Die After Irradiation? Time-Lapse Studies of Cells in Culture
- Modes of Cell Death by Anticancer Agents: The Crucial Importance of Dose