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Pharmaceutical Reference Guide from C.H.I.P.S.

Biodegradable Hydrogels for Drug Delivery
by Kinam Park

This reference provides an in-depth investigation of advances in biodegradable hydrogels.

Based on extensive research and experience, the book is the first to deal exclusively with this important area in drug delivery.

A valuable guide for both student and experienced professional, it begins with a detailed introduction to current biodegradable hydrogel technology. Following chapters present advanced R&D, delivery systems, and more.

Contents

  1. Introduction
    Controlled Release Drug Delivery Systems
    Hydrogels
  2. Biodegradation
    Definitions of Biodegradation
    Mechanisms of Biodegradation
    Chemical Hydrolysis of Polymers
    Biodegradable Hydrogels
  3. Types of Biodegradable Hydrogels
    Hydrogels with Degradable Polymer Backbone
    Hydrogels with Degradable Crosslinking Agents
    Hydrogels with Degradable Pendant Chains
  4. Chemical Gels
    Polymerization in the Presence of Crosslinking Agents
    Crosslinking of Water-Soluble Polymers
  5. Physical Gels
    Thermoreversible Gelling System
    Thermoreversible Gelling Polysaccharides
    Physical Gelation by Ion Complexation
    Physical Gelation by Specific Interactions
    Determination of the Crosslink Density
  6. Chemically-Induced Degradation
    Chemically-Induced Hydrolysis in the Body
    Chemically-Induced Hydrolysis of Polyesters
    Polyester Hydrogels
  7. Enzyme-Catalyzed Degradation
    Properties of Enzymes
    Hydrolytic Enzymes in the Body
    Factors Influencing Enzyme-Catalyzed Reactions
    Enzyme-Catalyzed Degradation of Modified Proteins
    Enzyme-Catalyzed Degradation of Modified Polysaccharides
  8. Biodegradable Drug Delivery Systems
    Mechanisms of Drug Release
    Drug Release from Hydrogels with Biodegradable Backbones
    Drug Release from Hydrogels with Degradable Crosslinking Agents
    Drug Release from Hydrogels with Biodegradable Pendant Chains
  9. Future Development
    Drug Loading
    Drug Targeting
    Drug Release
    Degradation and Elimination
    The Use of Bioactive Polymers
Index

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Biodegradable Hydrogels for Drug Delivery
by Kinam Park
252 pages $194.95 + shipping
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