Chemical Stability of Pharmaceuticals provides a sound theoretical basis for understanding chemical kinetics and its uses in studying drug stability.

Chemical Stability of Pharmaceuticals treats the calculations, approximations, and estimates that are useful to the pharmacist in professional practice, and presents a collection of selected drug-stability data from the pharmaceutical literature.

This Handbook makes accessible to the pharmacist much of the information necessary to make pharmaceutical decisions about drug stability.

Contents

Principles

1. Introduction
2. Stability Calculations
3. Interpretation of Kinetic Data
4. Hydrolysis and Other Acyl Transfers
5. Oxidation and Photolysis
6. Solid-State Chemical Decompostion
7. Strategy and Tactics of Stability Testing

Stability Monographs

Acetaminophen - Warfarin (alphabetically arranged)

Appendices

• Units and Dimensions
• Physical Constants
• Ion Product of Quality
• Q Values
• Time Unit Conversions
• Temperature Conversions
• Summary of Useful Formulas
• Problems

Index

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