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Practical Vitamin Reference from C.H.I.P.S.

Chemistry and Biochemistry of B12
edited by Ruma Banerjee

There have been dramatic advances in the field of researching Vitamin B12, and those advances have served to revitalize interest in Vitamin B12 among biochemists, organic and inorganic chemists, microbiologists, structural biologists, and many other science professions.

This book offers one major reference work that unites all of the vital discoveries about Vitamin B12, and its numerous essential functions.

Contents

  1. Chemistry of B12
    1. B12 History
    2. X-ray Crystallography of B12
    3. X-Ray Absorption Spectorscopy of B12: Structural Changes of Intermediate States
    4. Electronic Structure and Spectra of B12: From Trans Effects to Protein Conformation I
    5. Electronic Structure and Spectra of B12: From Trans Effects to Protein Conformation II
    6. EPR Spectroscopy of B12-Dependent Enzymes
    7. NMR Spectroscopy of B12
    8. Vibrational Spectroscopy of B12 and Related Compounds
    9. Magnetic Field Dependence of Cobalamin Photochemistry and Enzymes
    10. Stereospecificity of the Coenzyme B12 Catalyzed Rearrangements and the Role of Negative Catalysis
    11. Modeling the Structure of Cobalt Corrins by Molecular Mechanics and Molecular Dynamics Methods
    12. B12 Electrochemistry and Organometallic Electrochemical Synthesis

  2. Biochemistry and Biology of B12
    1. B12 and Nutrition
    2. Inborn Errors of Cobalamin Metabolism
    3. Diagnostic and Therapeutic Analogs of Cobalamin
    4. Intrinsic Factor and Haptocorrin and Their Receptors
    5. Transcobalamin II
    6. Mammalian Receptors of Vitamin B12-Binding Proteins
    7. Cobalamin Transport in Bacteria
    8. Biosynthesis of B12 in the Aerobic Organism Pseudomonas denitrificans
    9. B12 Biosynthesis: The Anaerobic Pathway
    10. Biosynthesis of the 5-6 Dimethylbenzimidazole Moiety of Cobalamin and of the Other Bases Found in Natural Corrinoids
    11. Regulation of Adenosylcobalamin Biosynthesis in Salmonella typhimurium
    12. X-ray Crystallography of B12 Enzymes: Methylmalonyl-CoA Mutase and Methionine Synthase
    13. The Acetogenic Corriniod Proteins
    14. The Role of Corrinoids in Methanogenesis
    15. Methionine Synthase
    16. Methylmalonyl-CoA Mutase
    17. Ribonucleotide Reductases
    18. Glutamate Mutase and 2-Methyleneglutarate Mutase
    19. Diol Dehydrase and Glycerol Dehydrase
    20. Ethanolamine Ammonia-Lyase
    21. Anomutases
    22. Isobutyryl-CoA Mutase
    23. Reductive Dehalogenases

Index

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Chemistry and Biochemistry of B12
edited by Ruma Banerjee
921 pages $364.00 + shipping
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