Chiral Drugs

edited by
Cynthia A. Challener

Chiral Drugs is a comprehensive listing of over 2,500 chiral drugs, classified by therapeutic class, and including structures and physical properties for each entry in the listing.

Part One contains four chapters which provide an introduction to topics relevant to the field of chiral chemistry and includes a brief overview of chirality, a short discussion on the current market drivers in the area of chiral chemistry, and a basic presentation of the various sources and methods for obtaining chiral compounds.

Part Two presents entries for over 2,500 chiral drugs, classified by therapeutic class.

When available, each main entry provides:

• The chemical name and a list of trade names and synonyms
• The CAS Registry Number
• The European Inventory of Existing Commercial Chemical Substances (EINECS) number
• The Merck Index (12th edition) number

The physical properties, including specific rotation, of each compound are described and indicated applications are presented. The structure of nearly every compound is provided, and the manufacturers and suppliers of the compounds are also given. Indexes, including a master index of names and synonyms and an index of custom manufacturing services for production of chiral compounds, are appended.

Chiral Drugs provides an introduction to the types of sources and methods currently in use for obtaining chiral molecules and is an invaluable resource for researchers in the pharmaceutical and biotechnology sectors as well as to those working in the basic biochemical sciences.

Contents

How to Use This Book
Glossary of Units
Abbreviations and Symbols

1. Chirality
   1. Overview of Chirality.
   2. Drivers for the Chiral Market.
   3. Sources of Chiral Compounds.
   4. Methodologies for Obtaining Chiral Compounds: Some Examples.

2. Main Entries

3. Indexes
   • CAS Registry Number Index.
   • EINECS Number Index.
   • Name and Synonym Index.

4. Manufacturer and Supplier Directory

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