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Drug Design and Development Handbook
from C.H.I.P.S.

Chirality
in Drug Design
and Development

edited by Indira K. Reddy
and Reza Mehvar

Covering every essential element in the development of chiral products, Chirality in Drug Design and Development provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals—supporting researchers as they critically evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds.

Contents

  • Effects of Crystal Structure and Physical Properties on the Release of Chiral Drugs
  • Use of Chiral Excipients in Formulations Containing Chiral Drugs
  • Transport of Chiral Molecules Across the Skin
  • Stereoselective Drug Delivery through Prodrug Approach
  • Stereoselectivity in Drug Action and Disposition: An Overview
  • Stereoselectivity in Pharmacokinetics and Pharmacodynamics: Selected Classes of Drugs
  • Stereospecific Pharmacokinetics and Pharmacodynamics: Cardiovascular Drugs
  • Chiral Inversion
  • Bioequivalency Determination of Racemic Drug Formulations: Is Stereospecific Assay Essential?
  • Regulatory Considerations in Drug Development of Stereoisomers

Index

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Chirality in Drug Design and Development
edited by Indira K. Reddy and Reza Mehvar
1,200 pages • $188.95 + shipping

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