Dermatologic, Cosmeceutic, and Cosmetic Development provides information on current pharmaceutical and cosmetic practices in the management of both major and minor skin disorders, and gives an expansive overview of novel drugs and therapies used to treat these conditions.

Dermatological, Cosmeceutic, and Cosmetic Development covers:

• the efficiency and delivery of topical therapies - including various pharmaceutical therapies
• the range of skin disorders, drugs used to manage the disorders, and the site where the effect is sought
• how percutaneous absorption is affected by age, skin, site, race, skin disease and damage and product form
• major skin diseases and injuries pertaining to wounds and burns with particular emphasis on novel treatment approaches
• and more!

Contents

Introduction

1. Skin structure, pharmaceutics, cosmetics, efficacy and toxicology of topically applied agents

Part I: Skin Disorders and Therapies

2. Drugs used for skin diseases
3. Treatment of dermatitis
4. Evolution of cosmetics to cosmeceutics and its application to skin disorders including ageing and blemishes
5. Biology of skin pigmentation and cosmetic skin color control
6. Evidence based cosmeceutical therapy

Part II: Specific Factors Affecting Targeting and Efficacy

7. Skin Hydration—a key determinant in topical absorption
8. Epidemiology of skin barrier function: host and environment factors
9. Permeability through diseased and damaged skin
10. Targeting the pilosebaceous gland
11. Drug penetration enhancement through human nail and skin

Part III: Topical Pharmaceuticals, Formulations and Indications

12. Getting the dose right in dermatological therapy
13. Drugs for pain and inflammation
14. Novel topically active anti-inflammatory and anti-microbial compounds for use in acne
15. Codrugs: potential therapies for dermatological diseases
16. Topical therapeutic agents used in wound care
17. Established and Emerging Oral Antifungals in Dermatology
18. Hydroxyacids and retinoids in cosmetic products

Part IV: Topical Cosmeceuticals, Formulations and Indications

19. Natural ingredients used in cosmeceuticals
20. The influence of formulation design on the clinical performance of topically applied formulations
21. Dry skin and moisturizers
22. Antioxidants in the skin: dermatological and cosmeceutical aspects
23. Absorption and evaporation of volatile compounds applied to skin
24. Efficacy, absorption and safety of essential oils
25. Sunscreens: efficacy, skin penetration and toxicological aspects

Part V: Safety Considerations

26. Efficacy and safety of Tea Tree and other oils
27. Safety assessments based on exposure, penetration and toxicity considerations

Part VI: Skin Assessment

28. Non-invasive evaluation of skin in the cosmetic industry
29. Application of in vivo laser scanning microscopy for skin analysis in dermatology and cosmetology

Part VII: Improving Therapeutic Outcomes Using Chemical Techniques

30. Chemical penetration enhancement: possibilities and problems
31. Multicomponent formulations of chemical penetration enhancers

Part VIII: Improving Therapeutic Outcomes Using Physical Techniques

32. Iontophoresis
33. DNA transfer in the skin
34. Pressure waves for transdermal drug delivery
35. Microneedle arrays as transcutaneous delivery devices
36. Needle-free ballistic delivery of powdered immunotherapeutics to the skin using supersonic gas flow

Index

click here to see books • videos • cd-roms of related interest