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DNA Methylation Basic Mechanisms
by W. Doerfler

DNA Methylation Basic Mechanisms is written by experts in the realm of research on basic mechanisms of DNA methylation and its role in biology and pathogenesis.

Contents

Introduction

  • The Almost-Forgotten Fifth Nucleotide in DNA: An Introduction

Pattern Formation

  • Replication and Translation of Epigenetic Information
  • DNA Methyltransferases: Facts, Clues, Mysteries
  • DNA Methylation in Plants

Determinant of Promoter Activity

  • De Novo Methylation, Long-Term Promoter Silencing, Methylation Patterns in the Human Genome, and Consequences of Foreign DNA Insertion

DNA Methyltransferases

  • Establishment and Maintenance of DNA Methylation Patterns in Mammals
  • Molecular Enzymology of Mammalian DNA Methyltransferases

Epigenetic Phenomena

  • Familial Hydatidiform Molar Pregnancy: The Germline Imprinting Defect Hypothesis?
  • Dual Inheritance

Mutagenesis and Repair

  • Mutagenesis at Methylated CpG Sequences
  • Cytosine Methylation and DNA Repair

Index

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DNA Methylation Basic Mechanisms
by PW. Doerfler
2006 • 321 pages • $154.00 + shipping
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