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Fungal Infections Reference
from C.H.I.P.S.

Fungal Pathogenesis
Principles and Clinical Applications
edited by Richard A. Calderone

Fungal Pathogenesis offers a current and concise survey of human pathogenic fungi.

Covers:

  • virulence factors host responses and recognition treatment and diagnosis of infections invasive enzymes intracellular survival morphogenesis adaptation properties of major fungal pathogens that contribute to disease

Contents

  1. What Makes Fungi Virulent?

    1. Host Recognition by Human Fungal Pathogens
    2. Genetic Basic of Pathogenicity in Cryptococcus neoformans
    3. Secretory Proteins in Fungal Virulence
    4. Histoplasma capsulatum: Diary of an Intracellular Survivor
    5. Dimorphism in Human Pathogens
    6. Signaling and the Biology of Human Fungal )Pathogens
    7. Adaptation of Fungi to Alterations in Ambient pH
    8. Molecular Biology of Switching in Candida
    9. Pathogenic Properties of Blastomyces dermatitidis
    10. Paracoccidioides brasiliensis: Virulence and Host Response
    11. Pneumocystis carinii
    12. Genomics in Fungal Pathogenesis

  2. Host Responses to Pathogenic Fungi/Immunoprotection

    1. Cell-Modified Immunity and Endemic Mycoses
    2. Humoral Immunity and Cryptococcus neoformans
    3. Vaccines, Antibodies, and passive Immunity in Candidiasis
    4. Vaccines for Histoplasmosis
    5. Coccidioidomycosis: Pathogenesis, Immune Response, and Vaccine Development
    6. Innate Immunity Against Fungal pathogens
    7. Immune Reconstitution Against human Mycoses
    8. Mucosal Infection and Immunity in Candidiasis
    9. Systemic Immunity in Candidiasis
    10. Cell Wall of Aspergillus fumigatus: Structure, Biosynthesis, and Role in Host-Fungus Interactions
    11. Cryptococcus neoformans and Macrophages

  3. Treatment and Patient Management

    1. Antifungals Currently Used in the Treatment of Invasive fungal Diseases
    2. Antifungal Drug Targets: Discovery and Selection
    3. Drug Resistance Mechanisms of Human pathogenic Fungi
    4. Antifungal Susceptibility Testing: Clinical Interpretations and Utility

  4. The Diagnostic Laboratory

    1. Molecular Diagnosis of Fungal Infections
    2. Serological Approaches to the Diagnosis of Invasive Fungal Infections
    3. Molecular Typing and Epidemiology of Candida spp. and Other Important Human Fungal Pathogens
    4. Strain Variation and Clonality in Candida spp. and Cryptococcus neoformans
    5. New and Emerging pathogens: What's a Lab to Do?

Index

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Fungal Pathogenesis
Principles and Clinical Applications
edited by Richard A. Calderone and Ronald L. Cihlar

762 pages $228.95 + shipping
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