Drug Delivery Reference from C.H.I.P.S.

Handbook of Pharmaceutical Controlled Release Technology
edited by Donald L. Wise

The Handbook of Pharmaceutical Controlled Release Technology reviews the design, fabrication, methodology, administration, and classifications of various drug delivery systems, including matrices, and membrane controlled reservoir, bioerodible, and pendant chain systems.

Contains cutting-edge research on the controlled delivery of biomolecules!

Discussing the advantages and limitations of controlled release systems, the Handbook of Pharmaceutical Controlled Release Technology

  • Covers oral, transdermal, parenteral, and implantable delivery of drugs
  • Discusses modification methods to achieve desired release kinetics
  • Highlights constraints of system design for practical clinical application
  • Analyzes diffusion equations and mathematical modeling
  • Considers environmental acceptance and tissue compatibility of biopolymeric systems for biologically active agents
  • Evaluates polymers as drug delivery carriers
  • Describes peptide, protein, micro-, and nanoparticulate release systems
  • Examines the cost, comfort, disease control, side effects, and patient compliance of numerous delivery systems and devices
  • And more!


  1. Polymers as Drug Delivery Carriers
    • Hydrophilic Cellulose Derivatives as Drug Delivery Carriers: Influence of Substitution Type on the Properties of Compressed Matrix Tablets
    • Poly(Vinyl Alcohol) as a Drug Delivery Carrier
    • Development of Acrylate and Methacrylate Polymer Networks for Controlled Release by Photopolymerization Technology
    • Smart Polymers for Controlled Drug Delivery
    • Complexing Polymers in Drug Delivery
    • Polylactic and Polyglycolic Acids as Drug Delivery Carriers
    • Use of Infrared and Raman Spectroscopy for Characterization of Controlled Release Systems
    • Accurate Models in Controlled Drug Delivery Systems

  2. Mechanism-Based Classification of Controlled Release Devices
    • Drug Release from Swelling-Controlled Systems
    • Superporous Hydrogels as a Platform for Oral Controlled Drug Delivery
    • Osmotic Implantable Delivery Systems
    • Bioadhesive Controlled Release Systems

  3. Micro- and Nanoparticulate Release Systems
    • Microencapsulation Technology: Interfacial Polymerization Method
    • Nanoparticulate Controlled Release Systems for Cancer Therapy
    • Microencapsulation Using Coacervation/Phase Separation: An Overview of the Technique and Applications
    • Microsphere Preparation by Solvent Evaporation Method
    • Nanosuspensions—A Formulation Approach for Poorly Soluble and Poorly Bioavailable Drugs
    • Large-Scale Production of Solid Lipid Nanoparticles (SLN) and Nanosuspensions (DissoCubes)
    • Solid Lipid Nanoparticles (SLN) as a Carrier System for the Controlled Release of Drugs
    • Stability of Encapsulated Substances in Poly(Lactide-co-Glycolide) Delivery Systems
    • Development of Polysaccharides as Novel Drug Carrier Systems

  4. Classification of Controlled Release Devices According to Administration Site
    • An Overview of Controlled Release Systems
    • Research and Development Aspects of Oral Controlled-Release Dosage Forms
    • A Gastrointestinal Retentive Microparticulate System to Improve Oral Drug Delivery
    • In Vitro-In Vivo Correlations in the Development of Solid Oral Controlled Release Dosage Forms
    • Gamma Scintigraphy in the Analysis of the Behavior of Controlled Release Systems
    • Electrically Assisted Transdermal Delivery of Drugs
    • A Novel Method Based on Artificial Neural Networks for Optimizing Transdermal Drug Delivery Systems
    • Transdermal Drug Delivery by Skin Electroporation
    • Enhancement of Transdermal Transport Using Ultrasound in Combination with Other Enhancers
    • Electrotransport Systems for Transdermal Delivery: A Practical Implementation of Iontophoresis

  5. Peptide and Protein Release Systems
    • Controlled Release Protein Therapeutics: Effects of Process and Formulation on Stability
    • Solid-State Chemical Stability of Peptides and Proteins: Application to Controlled Release Formulations
    • Growth Factor Release from Biodegradable Hydrogels to Induce Neovascularization
    • Biopolymers for Release of Interleukin-2 for Treatment of Cancer

  6. Medical Applications of Drug Delivery
    • Osmotic Drug Delivery from Asymmetric Membrane Film-Coated Dosage Forms
    • Controlled Release Pain Management Systems
    • Biodegradable Systems for Long-Acting Nestorone
    • Preparation and Evaluation of Buprenorphine Microspheres for Parenteral Administration
    • Prolonged Release of Hydromorphone from a Novel Poly(Lactic-co-Glycolic) Acid Depot System: Initial In Vitro and In Vivo Observations
    • Incorporation of an Active Agent into a Biodegradable Cement: Encapsulation of the Agent as Protection from Chemical Degradation During Cure and Effect on Release Profile
    • The Pharmacoeconomic Value of Controlled Release Dosage Forms

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Handbook of Pharmaceutical
Controlled Release Technology

edited by Donald L. Wise
904 pages • $278.95 + shipping

Texas residents please add 6.75 % sales tax

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