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Iminosugars handbook from C.H.I.P.S.

Iminosugars
From Synthesis to Therapeutic Applications
edited by Philippe Compain

Iminosugars: From Synthesis to Therapeutic Applications provides an up-to-date account of many contemporary aspects of iminosugars from organic synthesis to clinical studies.

Features:

  • An up-to-date account of many contemporary aspects of iminosugars from organic synthesis to clinical studies
  • Iminosugars are lead compounds for drug development in a variety of therapeutic areas
  • Contributions by the major world experts in the field
  • A table correlating the structures of all reported iminosugars with their biological activities, whenever such data are available

Contents

  1. Iminosugars: past, present and future
  2. Naturally occurring iminosugars and related alkaloids: structure, activity and applications
  3. General strategies for the synthesis of iminosugars and new approaches towards iminosugar libraries
  4. Iminosugar C-glycosides: synthesis and biological activity
  5. Imino-C-disaccharides and analogues: synthesis and biological activity
  6. Isofagomine, noeuromycin and other 1-azasugars, iminosugar related glycosidase inhibitors
  7. Iminosugar-based glycosyltransferase inhibitors
  8. Transition state analogue inhibitors of N-Ribosyltransferases
  9. Iminosugars as antiviral agents
  10. Iminosugars as active-site-specific chaperones for the treatment of lysosomal storage disorders
  11. Iminosugar inhibitors for substrate reduction therapy for the lysosomal glycosphingolipidoses
  12. Iminosugar-based antitumoural agents
  13. Medicinal use of iminosugars
  14. Tables of iminosugars, their biological activities and their potential as therapeutic agents

Index

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Iminosugars
From Synthesis to Therapeutic Applications
edited by Philippe Compain

2008 467 pages $169.00 + shipping
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