C.H.I.P.S. HOME PAGE
PHARMACEUTICAL CATALOG
TITLE LIST
MANUAL ORDER FORM
ONLINE ORDER FORM
QUESTIONS COMMENTS

Pharmaceutical Book from C.H.I.P.S.

Medicinal Chemistry of Bioactive Natural Products
by Xiao-Tian Liang

Medicinal Chemistry of Bioactive Natural Products provides a much-needed survey of bioactive natural products and their applications in medicinal chemistry.

Features:

  • Features articles by some of the world's leading scientists in the field on discovery, structure elucidation, and elegant synthetic strategies—developed for natural products
  • Guides the reader to the key developments in the field
  • Serves as a handy resource for researchers in their own work developing pharmaceuticals, and as an inspiring introduction for young scientists to the dynamic field of bioactive natural products research

Contents

The Chemistry and Biology of Epothilones--Lead Structures for the Discovery of Improved Microtubule inhibitors

  • Biological effects of Epo B.
  • Epothilone analogs and SAR studies.
  • Pharmacophore modelling and conformational studies.
  • Epothilone analogs in clinical development

The Chemistry and Biology of Vancomycin and Other Glycopeptide Antibiotic Derivatives

  • Classification of Glycopeptide Antibiotics.
  • Mode of Action.
  • Glycopeptide resistance.
  • Biosynthesis.
  • Total synthesis.
  • Glycopeptides as Chiral Selectors in Chromatography and Capillary Electrophoresis.
  • Structural Modifications of Glycopeptide Antibiotics and Structure Activity Relationship (SAR) Studies.
  • Modifications of Glycopeptide Antibiotics

Structure Modifications and Their Influences on Antitumor and Other Related Activities of Taxol and Its Analogues

  • Discovery and research and development of Taxol®.
  • Paclitaxel analogues active against sensitive tumor cells.
  • Exploration on mechanism of paclitaxel related to tubulin binding and quest for its pharmacophore.
  • Natural taxanes and semi-synthetic taxoids overcoming multi-drug resistance (MDR).
  • Design, synthesis and pharmacological activity of prodrugs of paclitaxel.
  • Other biological actions of paclitaxel--Apoptosis and immune stimulation.
  • New anti-microtubule molecules mimicking action of paclitaxel

The Overview of Studies on Huperzine A: A Natural Drug for the Treatment of Alzheimer?s Disease

  • Profiles of HA .
  • Plant resources.
  • Pharmacology.
  • Clinical trials .
  • Synthesis of HA and its analogues.
  • Structural biology .
  • ZT-1: New generation of HA ACHEI

Qinghaosu (artemisinin)---A Fantastic Antimalarial Drug from a Traditional Chinese Medicine

  • Qinghaosu and qinghao (Artemisia annua L. composites).
  • Reaction of qinghaosu.
  • Chemical synthesis and biosynthesis.
  • Derivatives and antimalarial activity .
  • Pharmacology and Chemical biology of qinghaosu and its derivatives

Progress of Studies on the Natural Cembranoids from the Soft Coral Species of Sarcophyton Genus

  • Cembrane-type constituents from Sarcophyton genus.
  • Physiological action of sarcophytol A and Sarcophytol B .
  • Total synthesis of the natural cembranoids .
  • Studies on novel macrocyclization methods of cembrane-type diterpenoid

Medicinal Chemistry of Ginkgolides from Ginkgo biloba

  • Ginkgolides and the PAF Receptor.
  • Ginkgolides and Glycine Receptors.
  • Various Effects of Ginkgolides

Recent Progress in Calophyllum Coumarins as Potent Anti-HIV Agents

  • Anti-HIV-1 activity of Calophyllum coumarins.
  • Pharmacology of Calanolides.
  • Preparation of Calophyllum coumarins.
  • Structure modification of Calanolides

Recent Progress and Prospects on Plant-derived Anti-HIV Agents and Analogs

  • Khellactone Coumarin Analogs as Anti-HIV Agents.
  • Biphenyl Derivatives as Anti-HIV Agents.
  • Triterpene betulinic acid derivatives as anti-HIV agents

Recent Progress on the Chemical Synthesis of Annonaceous Acetogenins and their structurally modified mimics

  • Total synthesis of mono-THF acetogenins .
  • Total synthesis of bis-THF acetogenins.
  • Total synthesis of THP-containing acetogenins.
  • Design and synthesis of mimics of acetogenins

Index

click here to see books of related interest

ORDER NOW

Medicinal Chemistry of Bioactive Natural Products
by Xiao-Tian Liang
2006 • 460 pages • $98.95 + shipping
Texas residents please add 6.75 % sales tax

Go to Top of Page

copyright © 1997-2012 Culinary and Hospitality Industry Publications Services