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Molecular Analysis Reference from C.H.I.P.S.

Microarray Analysis
by Mark Schena

Microarray Analysis is the first textbook in this revolutionary new field of study!

This comprehensive and multidisciplinary reference begins with an introduction to microarray analysis, and explores basic chemistry, biochemistry, and genomics. Separate chapters are devoted to surface chemistry, target and probe preparation, microarray manufacture and detection, and data analysis and modeling. Methodology, cleanroom technology, gene expression profiling, genetic screening and diagnostics, and novel technologies round out this classic textbook.

  • Rapidly teaches students the fundamentals of microarrays
  • Describes protein microarrays and other rapidly advancing forefronts
  • Builds a conceptual foundation for the entire field
  • Presents commercial opportunities in microarray science
  • Emphasizes the exciting clinical applications of microarrays

Microarray Analysis provides any science student or professional all the tools required to understand this revolutionary technology.

Contents

  1. Introduction to Microarray Analysis.
  2. Introduction to Chemistry.
  3. Basics of Biochemistry.
  4. Genes and Genomes.
  5. Microarray Surfaces.
  6. Targets and Probes.
  7. Microarray Manufacturing.
  8. Microarray Detection.
  9. Microarray Informatics.
  10. Methodological Architecture.
  11. Cleanroom Technology.
  12. Gene Expression Profiling.
  13. Genetic Screening and Diagnostics.
  14. Novel Microarray Technologies.
  15. Commercial Opportunities A to Z.
  16. Future Trends: Chips in the Clinics

Appendix A: Prefixes
Appendix B: Unit Abbreviations
Appendix C: Technical Abbreviations
Appendix D: Conversions
Appendix E: Nucleic Acid Molecular Weight Calculations
Appendix F: Microarray Spot Area Calculations
Appendix G: Microarray Fluor Density Calculations
Appendix H: Microarray Target Density Calculations
Appendix I: Microarray Web Sites

Glossary
Answers
Index

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Microarray Analysis
by Mark Schena
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