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Microbiology Book from C.H.I.P.S.

New Strategies Combating Bacterial Infection
edited by Iqbal Ahamad

New Strategies Combating Bacterial Infection adopts a novel approach, focusing on combating multi-drug resistance in bacteria by developing antibacterials with new target sites, using new advances in drug discovery as well as natural products.

Divided into three sections, the first describes the problem of drug resistance and the need for new drugs, while the second treats recent trends and new classes of drugs, including relevant developments in transcriptomics and proteomics leading to new antimicrobial drug discovery, and a new generation of antibiotics and non-antibiotics.

The third section on natural products discusses the antibacterial action of phytocompounds, plant extracts, essential oils and honey as well as the role of probiotics in bacterial infections.

Contents

1. Molecular Mechanisms of Antibiotic Resistance: The Need for Novel Antimicrobial Therapies

  • Molecular Mechanisms of Resistance
  • B-Lactams
  • Glycopeptides
  • Lantibiotics
  • Aminoglycosides
  • Macrolides
  • Tetracyclines
  • Fluoroquinolones
2. Novel Approaches to Combat Drug-Resistant Bacteria

  • Approaches to Antibacterial Drug Discovery and Combating the Problem of Drug Resistance
  • Combination Drug Therapy
  • Strategies to Target Mechanism of Drug resistance
  • Quorum Sensing Inhibition: A Novel Anti-Infective Drug Target
  • Phage Therapy: An Alternative Therapy
  • Antibiotic Use Policy: Practical Management of the Problem of Antibiotic Resistance
3. Promising Current Drug Candidates in Clinical Trials and Natural Products Against Multidrug-resistant Tuberculosis

  • Current MDR-TB Treatment
  • Current Drugs in Development Against MDR-TB
  • Natural Products Against MDR-TB
4. Non-antibiotics - An Alternative for Microbial Resistance: Scope and Hope

  • Historical Development: Non-antibiotics with Antimicrobial Potential
  • Psychotherapeutics as N on-antibiotics
  • Sedatives and Tranquilizers as Non-antibiotics
  • Antihistaminics as Non-antibiotics
  • In vitro and In vivo Antimicrobial Potential of Non-antibiotics
  • Single and Combined Activity Against Bacteria
  • Synergism and 'Reversal of Resistance': A Special Synergy
  • Mechanism of Action of Non-antibiotics
5. Use of Natural Products to Combat Multidrug-Resistant Bacteria

  • Natural Product Development
  • MRSA
  • Natural Products for MDR Microorganisms
6. West African Plans and Related Phytocompounds with Anti-Multidrug-Resistance Activity

  • MDR Bacteria in West Africa
  • Plants Used in Bacterial Disease treatment in West Africa
  • West African Medicinal Plants with Activity against MDR Bacteria
  • Metabolites Isolated from West African Medicinal Plants Effective on MDR Bacteria
7. Essential Oils and New Antimicrobial Strategies

  • Introduction : Essential Oils
  • Biosynthetic Origin
  • Extraction of Essential Oils
  • Storage of Essential Oils
  • Chemical Analysis of Essential Oils
  • Physical Parameters
  • Olfactory Evaluation
  • Essential Oils as Antimicrobials
  • Antimicrobial Activity: Mode of Action
  • Antimicrobial Assays
  • Other Applications of Essential Oils
  • Toxicity of Essential Oils
  • Scope for Future Research
8. Application of Plant Extracts and Products in Veterinary Infections

  • Veterinary Infectious Diseases and their Significance
  • Plants as Sources of Antimicrobial Compounds
  • Antibiotic Resistance and the Impact of Antibiotic Feed Additives
  • Plants as Replacements for Antibiotic Feed Additives
9. Honey: Antimicrobial Actions and role in Disease Management

  • Nature of the Antimicrobial Activity of Honey
  • Spectrum and Potency of the Antimicrobial Activity of Honey
  • Other Actions
  • Clinical Uses of Honey as an Antimicrobial Agent
  • Clinical Evidence for Effectiveness of Honey on Infected Wounds
  • Resistant Bacteria
  • Benefits Apart from control of Infection in Topical treatment with Honey
10. Honey: Biological Characteristics and Potential role in Disease Management

  • biological Characteristics of Honey
  • Antibacterial Potential of Honey
  • Potential Use of Honey as an Antibacterial Agent
  • Use of Honey against Multidrug resistance
11. Probiotics: Benefits in Human Health and Bacterial Disease Management

  • Gut Microbiota
  • Probiotics, Intestinal Microbiota and Host Health
  • Studies on the Management and Prevention of Diseases
  • Clinical Prospects of Gut Microbiota Research
Index

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New Strategies Combating Bacterial Infection
edited by Iqbal Ahamad
2009 • 304 pages • $188.95 + shipping
Texas residents please add 6.75 % sales tax

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