This updated and expanded second edition covers all aspects of capsule technology, including history, standards, methods and equipment used in manufacture, filling, printing, weighing, cleaning and inspecting of both hard and soft capsules.

Pharmaceutical Capsules covers the history of medicinal capsules, methods and equipment used in manufacture and filling, the rationale for formulation, especially drug release from products, and industrial and official standards.

Pharmaceutical Capsules is an essential resource for all those involved in the development, manufacture and testing of capsules. It will also be valuable to pharmaceutical science students and regulatory authorities.

Contents

1. The History of the Medicinal Capsule
2. Gelatin: Manufacture and Physico-Chemical Properties
3. Gelatin Alternatives and Additives
4. Manufacture and Properties of Two-Piece Hard Capsules
5. Powder, Granule, and Pellet Properties for Filling of Two-Piece Hard Capsules
6. Dry Filling of Hard Capsules
7. Instrumented Capsule-Filling Machines and Simulators
8. Capsule Processing and Packing
9. Filling of Liquids and Semi-Solids into Hard Two-Piece Capsules
10. Technology to Manufacture Soft Capsules
11. Formulation and Physical Properties of Soft Capsules
12. Drug Release from Capsules
13. Capsule Standards

Index

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