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Pharmaceutical Photostability Handbook
from C.H.I.P.S.

Pharmaceutical Photostability and Stabilization Technology
edited by Joseph T. Piechocki

Pharmaceutical Photostability and Stabilization Technology clarifies the guidelines set by the International Conference on Harmonization (ICH) and provides a comprehensive background in the scientific principles involved in photostability testing.

Presenting the advantages and disadvantages of various procedures so the reader can select and utilize the most appropriate technique best-suited to their needs, Pharmaceutical Photostability and Stabilization Technology includes references to current literature in the field and offers an opinion on future opportunities and challenges.

Features:

  • assists in the selection of the most appropriate photon source and actinometer for specific applications
  • devotes an entire chapter on the study of chemical actinometry-a stable, self-standardizing method of radiation dosage assessment
  • focuses attention on molecular mechanisms and kinetics and their importance in the development of protective measures
  • offers reviews of the available testing chambers for pharmaceutical photochemical studies
  • details protective methods for all dosage forms useful in preventing photodegradation
  • includes information on the use, action, and methods of determination of the effectiveness and stabilization of sunscreens

Contents

  1. History of Pharmaceutical Photostability Development
  2. The ICH Photostability Guideline: A Discussion of Experimental Conditions.
  3. Terminology
  4. Basic Principles of Drug Photostability Testing
  5. Spectra
  6. Sources
  7. Glasses, Filters, and Containers
  8. Chemical Actinometry
  9. Radiometry/Photometry
  10. Sample Presentation for Photostability Studies: Problems and Solutions
  11. Determining the Kinetics and Mechanism of a Photochemical Reaction
  12. Unexpected Photochemistry in Pharmaceutical Products: A Review on the Role of Diluents, Excipients, and Product Components in Promoting Pharmaceutical Photochemistry
  13. Chambers and Mapping
  14. Current Methods for the Analytical Investigation of the Photodegradation of Active Pharmaceutical Ingredients and Products
  15. Photostabilization by Packaging
  16. Photostabilization of Solid and Semisolid Dosage Forms
  17. Photostability Studies of Solutions and Methods of Preventing Photodegradation
  18. Photostability of Cosmetic Screens
  19. Photodegradation and Photoprotection in Clinical Practice

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Pharmaceutical Photostability and
Stabilization Technology

edited by Joseph T. Piechocki
2006 445 pages $248.95 + shipping
Texas residents please add 6.75 % sales tax

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