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Medical Book from C.H.I.P.S.

Postmenopausal Osteoporosis
Hormones and Other Therapies
edited by A. R. Genazzani

Postmenopausal Osteoporosis has in-depth sections on the pathogenesis, epidemiology, and diagnosis of osteoporosis.

Features:

  • Published in association with International Menopause Society
  • Comprehensive
  • Focus on therapy
  • High-class, international authorship

Contents

Introduction

  1. Magnitude and impact of osteoporosis and fractures
  2. Impact of osteoporosis on quality of life and quality of life on osteoporosis: rationale and methodology for accurate assessment

Gonadal Steroids and The Pathogenesis of Osteoporosis

  1. Peptide hormones and osteocyte growth factors
  2. Steroids as regulators of osteoblastic function
  3. Steroids and the regulation of osteoclastic bone resorption
  4. Calcium and vitamin D: regulation of mineral homeostasis

Epidemiology

  1. Genetic determinates of bone mass
  2. Bone mineral acquisition during infancy & adolescence
  3. Style of life, physical activity and nutritional factors
  4. Postmenopausal osteoporosis & dental health

Diagnosis

  1. Bone densitometry and radiology
  2. Assessment of bone quality. Clinical, hormonal and biochemical evaluation.
  3. New techniques for the non-invasive assessment of bone quality
  4. Bone ultrasound

Pharmacological Prevention and Treatment

  1. Awareness of osteoporosis and related treatments
  2. Intervention thresholds for osteoporosis
  3. Vitamin D and calcium supplements
  4. Estrogen dose response in bone density and bone histology
  5. Effects of oral contraceptive preparation on hone health
  6. Hormone replacement therapy
  7. New physiologic approach to prevention of postmenopausal osteoporosis
  8. Selective estrogen receptor modulators
  9. Bisphosphonates in the management of osteoporosis
  10. Phytoestrogens: food or drug?
  11. Tibolone
  12. Understanding the role of aromatizable androgens in bone-sparing

Specific Aspects of Selected Therapies

  1. Strontium ranelate: a new first-line treatment for patients
  2. Reconciling risks and benefits of hormone replacement therapy in a single outcome: the QALY approach
  3. Prevent, treat and maintain: how to optimize the management of postmenopausal osteoporosis
  4. Transdermal hormone therapy: effects on bone
  5. Progestogens and bone
  6. Effect of different dose options of continuous combined hormone therapy on bone and bone marker N-terminal propeptide of type I procollagen: results from a long-term study on Finnish postmenopausal women
  7. The use of alendronate in osteoporosis treatment: 10-year experience

Index

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Postmenopausal Osteoporosis
Hormones and Other Therapies
edited by A. R. Genazzani

2006 320 pages $178.95 + shipping
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