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Pharmaceutical Book from C.H.I.P.S.

Protein Lipid Interactions
From Membrane Domains to Cellular Networks
edited by Lukas K. Tamm

Protein Lipid Interactions covers the interactions between proteins and lipids that make the fabric of biological membranes from every angle.

Features:

  • Examines the relevant hermodynamic and structural issues from a basic science perspective
  • Discuss biochemical and cell biological processes
  • Covers physical principles as well as mechanisms of membrane fusion and fission

Contents

How Lipids Share Proteins

  • Lipid Bilayers, Translocons, and the Shaping of Polypeptide Structure
  • Folding and Stability of Monomeric beta-Barrel Membrane Proteins
  • A Paradigm of Membrane Protein Folding: Principles, Kinetics and Stability of Bacteriorhodopsin Folding
  • Post-Integration Misassembly of Membrane Proteins and Disease

How Proteins Share Lipids

  • A Census of Ordered Lipids and Detergents in X-ray Crystal Structures of Integral Membrane Proteins
  • Lipid and Detergent Interactions with Membrane Proteins Derived from Solution Nuclear Magnetic Resonance

Membrane Penetration by Toxins

  • Lipid Interactions of a-Helical Protein Toxins
  • Membrane Recognition and Pore Formation by Bacterial Pore-forming Toxins
  • Mechanism of Membrane Permeation and Pore Formation by Antimicrobial Peptides

Mechanisms of Membrane Fusion

  • Cell Fusion in Development and Disease
  • Molecular Mechanisms of Intracellular Membrane Fusion
  • Interplay of Proteins and Lipids in Virus Entry by Membrane Fusion

Cholesterol, Lipid Rafts, and Protein Sorting

  • Protein-Lipid Interactions in the Formation of Raft Microdomains in Biololgical Membranes
  • Protein and Lipid Partitioning in Locally Heterogeneous Model Membranes

Targeting of Extrinsic Membrane Protein Modules to Membranes and Signal Transduction

  • In vitro and Cellular Membrane-binding Mechanisms of Membrane-targeting Domains
  • Structure and Interactions of C2 Domains at Membrane Surfaces
  • Structural Mechanisms of Allosteric Regulation by Membrane-binding Domains

Index

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Protein Lipid Interactions
From Membrane Domains to Cellular Networks
edited by Lukas K. Tamm

2005 4702 pages $229.00 + shipping
Texas residents please add 6.75 % sales tax

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