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Clinical Trials Science Book from C.H.I.P.S.

Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation
A Practical Guide to Analysis and Interpretation
by Stephen J. Walters

Quality of Life (QoL) outcomes or Person/Patient Reported Outcome Measures (PROMs) are now frequently being used in randomised controlled trials (RCTs) and observational studies.

Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation provides a practical guide to the design, analysis and interpretation of studies that use such outcomes.

  • Provides a user-friendly guide to the design and analysis of clinical trials and observational studies in relation to QoL outcomes.
  • Discusses the problems caused by QoL outcomes and presents intervention options to help tackle them.
  • Guides the reader step-by-step through the selection of appropriate QoLs.
  • Features exercises and solutions and a supporting website providing downloadable data files
Illustrated throughout with examples and case studies drawn from the author’s experience, Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation offers statisticians and clinicians guidance on choosing between the numerous available QoL instruments.

Contents

  1. Measuring Quality of Life
  2. Choosing a Quality of Life Measure for your Study
  3. Design and Sample Size Issues: How Many Subjects do I Need for my Study?
  4. Reliability and Method Comparison Studies for Quality of Life Measurements
  5. Summarizing, Tabulating and Graphically Displaying Quality of Life Outcomes
  6. Cross-Sectional Analysis of Quality of Life Outcomes
  7. Randomized Controlled Trials
  8. Exploring and Modelling Longitudinal Quality of Life Data
  9. Advanced Methods for Analysing Quality of Life Outcomes
  10. Economic Evaluations
  11. Meta-analysis
  12. Practical Issues
Appendicies
  • Examples of Questionnaires
  • Statistical Tables
Index

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Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation
A Practical Guide to Analysis and Interpretation
by Stephen J. Walters

2009 • 365 pages • $89.00 + shipping
Texas residents please add 6.75 % sales tax

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