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Somatostatin
Edited by Coimbatore B. Srikant

Somatostatin is written by expert(s) active in somatostatin research (experimental and/or clinical).

Somatostatin serves as the only single one-stop source of the most up to date information on the basic and clinical aspects of the biology of somatostatin and its receptors.

Contents

Somatostatin - General Biology

  1. Somatostatin Gene Structure and Regulation
  2. Processing and Intracellular Targeting of Somatostatin
  3. Cortistatin - A Novel Member of the Somatostatin Gene Family
  4. Molecular Evolution of Somatostatin Genes
  5. Altered Patterns of Growth Hormone Secretion in Somatostatin Knockout Mice

Expression and Function of Somatostatin Receptors

  1. Somatostatin Receptor Gene Family- Subtype Selectivity Ligand Binding
  2. Expression of Somatostatin Receptors in Human Tissues in Health and Disease
  3. Coexpression of Multiple Somatostatin Receptors in Individual Cells
  4. Somatostatin Receptor Subtype Selectivity for Cytotoxic and Cytostatic Signaling
  5. Somatostatin Receptor Signaling via Protein Tyrosine Phosphatases
  6. Expression and Function of Somatostatin and Its Receptos in Immune Cells
  7. Physiology of Somatostatin Receptors: From Genetics ot Molecular Analysis

Applications in Disease

  1. Somatostatin Receptor Imaging
  2. Somatostatin Analogs in the Treatment of Pituitary Tumors
  3. Somatostatin Receptor Targeted-Radio-Ablation of Tumors
  4. Somatostatin Analogue Therapy of Neuro-Endocrine Gastro-Entero Pancreatic Tumors
  5. Vascular Effects of Somatostatin
  6. The Use of Somatostatin Analogues in Diabetic Retinopathy

The Future

  1. Somatostatin and Its Receptors: Past, Present and the Future

Index

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Somatostatin
Edited by Coimbatore B. Srikant
2004 311 pages $148.00 + shipping
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