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Pharmacology Reference Book from C.H.I.P.S.

Textbook of Receptor Pharmacology
Second Edition
edited by by John C. Foreman

  • Contains two new chapters: Molecular Structure of Tyrosine Kinase Receptors and G-Proteins
  • Provides over a hundred diagrams and tables to aid illustration of concepts, practice problems to facilitate comprehension, and an index explaining the simple mathematics used in the text
  • Unites four major approaches in the study of receptors: molecular biology, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction systems
  • Includes an overview of the importance of receptors in drug development written by Nobel Laureate James W. Black
  • Constructs a logical introduction to the various approaches that can be taken to the study of drug receptors
  • Presents information from an international group of experts

The bestselling first edition of Textbook of Receptor Pharmacology originated from a renowned course in receptor pharmacology taught at the University College of London for the past three decades. Its innovative format united four major approaches to the study of receptors: molecular biology, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction systems. The second edition builds on this foundation.

The Second Edition streamlines the material and focuses on cell membrane receptors along with their immediate signal transducers. The section on the molecular structure of receptors reflects the advances in this area. This edition also includes two restructured new chapters, one on G-proteins and one on tyrosine kinases, as signal transductors. Several chapters also contain problems for students to solve as well as worked-out solutions.

The book contains over one hundred useful diagrams and tables to aid illustration of concepts and a helpful appendix explaining the simple mathematics used in the text. A time-saving resource and comprehensive textbook, Textbook of Receptor Pharmacology, Second Edition provides in-depth, up-to-date coverage of this still rapidly expanding research area that is both fundamental to the science of pharmacology and on the cutting edge of new drug development.

Contents

  1. Drug-Receptor Interactions
    • Classical Approaches to the Study of Drug-Receptor Interactions

  2. Molecular Structure of Receptors
    • Molecular Structure and Function of 7TM G-Protein Coupled Receptors
    • The Structure of Ligand-Gated Ion Channels
    • Molecular Structure of Receptor Tyrosine Kinases

  3. Ligand Binding Studies of Receptors
    • Direct Measurement of Drug Binding to Receptors

  4. Transduction of the Receptor Signal
    • Receptors Linked to Ion Channels: Mechanisms of Activation and Block
    • G Proteins
    • Signal Transduction through Protein Tyrosine Kinases

  5. Receptors as Pharmaceutical Targets
    • Receptors as Pharmaceutical Targets

Index

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Textbook of Receptor Pharmacology 2nd Edition
edited by John C. Foreman and Torben Johansen
304 pages $128.95 + shipping
Texas residents please add 6.75 % sales tax

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