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Thrombosis and Hemorrhage
Third Edition
by Joseph Loscalzo

Thrombosis and Hemorrhage authoritative text continues to provide a comprehensive and systematic review of the biology, pathobiology, and clinical disorders of the hemostatic system.

Thrombosis and Hemorrhage covers:

  • angiogenesis and vasculogenesis hemorrhagic complications of antithrombotic therapy
  • interactions of coagulation and fibrinolytic proteins with the vessel wall
  • less common thrombotic disorders

Contents

Coagulation and Fibrinolysis

  1. Coagulation Cascade: An Overview
  2. Molecular Genetics of Blood Coagulation
  3. Regulation of Coagulation
  4. The Tissue Factor Pathway of Coagulation
  5. Fibrin Formation and Stabilization
  6. Regulation of Fibrinolysis

Platelets

  1. Regulation of Megakaryopoiesis
  2. Platelet Morphology and Shape Change
  3. Platelet Membranes and Receptors
  4. Mechanisms of Platelets Activiation

Vessel Wall

  1. The Endothelium in Thrombosis and Hemorrhage
  2. Angiogenesis and Hemostasis
  3. Vascular Response to Injury
  4. Von Willebrand Factor
  5. Interactions of Coagulation and Fibrinolytic Proteins with the Vessel Wall
  6. Endothelium-derived Vassoactive Factors
  7. Rheology

Clinical Approach to Bleeding and Thrombosis

  1. Approach to Bleeding
  2. Approach to Thrombosis
  3. Assessment of Peripheral Arterial and Venous Thrombosis
  4. Laboratory Methods in Hemostasis

Quatitative Platelet Disorders

  1. Thrombotic Microangiopathies: Thrombotic Thrombocytopenic Purpura and the Hemolytic-Uremic Syndrome
  2. Alloimmune Thrombocytopenias
  3. Drug-induced Thrombocytopenias
  4. Immune Thrombocytopenic Purpura
  5. Thrombocytosis

Qualitative Platelet Disorders

  1. Congenital Disorders of Platelet Function
  2. Acquired Disorders of Platelet Function

Disorders of Coagulation Factors and Fibrinolysis

  1. Von Willebrand Disease
  2. Hemophilia-Factor VIII Deficiency
  3. Other Coagulation Factor Deficiencies
  4. Factor VIII and Other Coagulation Factor Inhibitors
  5. Antiphospholipid Syndrome and Lupus Anticoagulants

Thrombotic Disorders

Chapters 34-36

Other Disorders of Hemostasis

Chapters 37-43

Management of Bleeding

Chapters 44-46

Management of Thrombosis

Chapters 47-57

Index

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Thrombosis and Hemorrhage
Third Edition
by Joseph Localzo

1,142 pages $228.00 + shipping
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