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Pulmonary Medicine Book from C.H.I.P.S.

Ventilator-Induced Lung Injury
edited by Didier Dreyfuss

Ventilator-Induced Lung Injury surveys current best practices in the prevention and management of ventilator-induced lung injury (VILI).

Features:

  • Showcases the latest treatment regimens and applications with chapters by seasoned experts in the field
  • Studies the many aspects of VILI generation and development
  • Considers the physical and biological triggers of ventilator-induced lung injury
  • Details the use of modern imaging technologies for an improved understanding of VILI mechanisms, progression, and treatment
  • Describes methods to design clinical studies for the prevention of ventilator-associated lung injury

Contents

Introduction

  • Ventilator-Induced Lung Injury: From Bench to Bedside and Back Again

Acute Manifestations of Vili

  • Pathological Features of ARDS and VILI
  • Imaging Alveolar Mechanics During VILI
  • Response of Cellular Plasma Membrane to Mechanical Stress
  • Passive and Active Changes in Microcascular Permeability During Lung Distension
  • Meodynamic Interactions During VILI
  • Gene Expression During VILI
  • Lung Mechanics and VILI
  • Effects of Acute Lung Distension on the Cytokine Network

Subacute VILI

  • Inflammation Cascade During VILI
  • Apoptosis in the Lung and Remote Organs During VILI
  • Systemic Consequences of VILI/Evidence for Organ Failure Causation
  • Interaction of VILI with Previous Lung Alterations
  • Modulation of Lung Injury by Hypercapnia
  • Potential Implications of Genomics in the Prevention and Treatment of VILI

Clinical Implications of VILI

  • Lung Imaging of Ventilator-Associated Injury
  • The Future of Lung Imaging of VILI/VALI
  • Modulation of the Cytokine Network by Lung Protective Mechanical Ventilation Strategies
  • Role of Tidal Volume and of Peep in the Reduction of Ventilator-Associated Lung Injury
  • A Critical Review of Randomized Controls of Tidal Volume Reduction During ARDS

Prevention and Treatment of VILI

  • The Importance of Protocol-Directed Management for Research on Lung Protective Ventilation
  • How to Design Clinical Studies for the Prevention of Ventilator-Associated Lung Injury
  • Potential Benefits and Risks of Partial Liquid Ventilation During Acute Lung Injury
  • Prospects for Reduction of VILI with Surfactant
  • Rationale for HFO Ventilations in Acute Lung Injury

Index

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Ventilator-Induced Lung Injury
edited by Didier Dreyfuss
2006 776 pages $248.95 + shipping
Texas residents please add 6.75 % sales tax

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