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In Vivo MR Techniques in Drug Discovery and Development
edited by Nicolau Beckmann

In Vivo MR Techniques in Drug Discovery and Development illustrates the use of MR techniques throughout the drug discovery and development process, from target identification and validation to clinical studies.

Features:

  • Discusses applications for specific disease areas, emphasizing the advantages and limitations of the approaches
  • Covers both preclinical animal research and clinical studies
  • Includes an entire chapter devoted to high-throughput imaging of mice and another to the design of contrast agents for molecular imaging applications

Contents

  1. The Drug Discovery and Development Process: A Brief Overview
  2. The Drug Discovery and Development Process: Opportunities and Challenges for MR Techniques
  3. Imaging as Biomarker for Decision-Making in Drug Development
  4. Design of Contrast Agents for Molecular Imaging In Vivo
  5. Rapid Phenotyping of Mice with MRI
  6. Magnetic Resonance Imaging and Spectroscopy in Transgenic Mice Modeling Alzheimer's Disease
  7. Imaging Alzheimer's Disease with MRI
  8. MRI and MRS in Animal Models of Focal Cerebral Ischemia
  9. MRI in Clinical Studies of Stroke
  10. Pharmacologic Magnetic Resonance Imaging (phMRI)
  11. Brain fMRI in Clinical Pharmacological Studies
  12. Imaging Inflammatory Processes of the Brain: Multiple Sclerosis as an Example
  13. Functional and Molecular Magnetic Resonance Imaging of Preclinical Cancer Models in Drug Discovery and Development
  14. MR for Clinical Pharmacological Studies in Cancer
  15. Molecular Imaging in Cancer Therapies of the Future
  16. Cardiac MR Techniques Applied to Small Rodents
  17. Cardiac MRI Techniques for Clinical Drug Trials
  18. Lung MRI in Small Rodents as a Tool for the Evaluation of Drugs in Models of Airways Diseases
  19. Clinical Applications of MRI in Respiratory Diseases
  20. MR in Preclinical Diabetes and Obesity Drug Discovery
  21. MR in Clinical Diabetes Research and Drug Trials
  22. Rheumatoid and Osteoarthritis: Preclinical Applications of In Vivo MR
  23. Rheumatoid and Osteoarthritis: Clinical Applications
  24. In Vivo Magnetic Resonance Techniques in Transplantation Research
  25. MR Imaging and the Development of Stem Cell-Based Therapies
  26. MRI in Pharmaceutical Safety Assessment
  27. In Vivo MR in Pharmaceutical Research: Essential or Nice to Have

Index

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In Vivo MR Techniques in Drug Discovery and Development
edited by Nicolau Beckmann
2006 592 pages $228.95 + shipping
Texas residents please add 6.75 % sales tax

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