Strategies for Diagnosis and Management
edited by Renu Virmani
The Vulnerable Atherosclerotic Plaque presents contributions from the best investigators in the field, skillfully edited for easy reading and lavishly illustrated with high-quality, full-color images.
The Vulnerable Atherosclerotic Plaque concentrates on:
- Pathology of vulnerable plaque
- Triggers for plaque rupture
- Imaging of unstable plaque
- Management of vulnerable plaques
Contents
- History of atherosclerosis and vulnerable plaque research
Pathology
- The pathology of vulnerable plaque
- Plaque rupture
- Plaque erosion
- Pathogenesis and significance of calcification in coronary atherosclerosis
- Adventitial and periadventitial fat inflammation and plaque vulnerability
- Murine models of advanced atherosclerosis
Triggers for plaque rupture
- Physical and mechanical stress
- Inflammation and matrix metalloproteinases
- Apoptosis in atherosclerosis
Diagnosis
- Emerging biomarkers of instability
- Ultrasonic detection of coronary disease
- Intravascular ultrasound for plaque characterization
- Magnetic resonance imaging and intravascular magnetic resonance imaging
- Radionuclide imaging
- Near-infrared spectroscopy
- Intravascular thermography
- Optical coherence tomography
- Intravascular palpography
- Coronary computed tomography for the detection of atherosclerotic plaque
Management
- New developments in treatment of vulnerable plaques
- Photodynamic therapy
- Thermal stabilization of vulnerable plaques
- An interventionalist’s perspective
- Genetic modulation of vulnerable plaques
Index
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