Spectroscopic Analysis Reference from C.H.I.P.S.

Two-Dimensional Correlation Spectroscopy
Applications in Vibrational and Optical Spectroscopy
by Isao Noda
and Yukihiro Ozaki

In Chapter 1, some historical perspectives and an overview of the field of perturbation-based 2D correlation spectroscopy is provided. Chapter 2 covers the central theoretical background of the two-dimensional correlation method. Chapter 3 provides a rapid and simple computational method for obtaining 2D correlation spectra from experimentally obtained spectral data set, followed by the practical considerations to be taken into account for the 2D correlation analysis of real-world spectral data in Chapter 4.

Chapter 5 introduces the concept of sample-sample correlation and hybrid correlation, and Chapter 6 explores the relationship between 2D correlation spectroscopy and classical statistical and chemometrical treatments of data. Chapter 7 examines other types of 2D spectroscopy, such as nonlinear optical 2D spectroscopy based on ultra fast laser pulses, 2D mapping of correlation coefficient, and newly emerging variant forms of 2D correlation analyses, such as moving-window correlation and model based correlation method.

The remaining chapters of the book are devoted to specific application examples of 2D correlation spectroscopy illustrating how the technique can be utilized in various aspects of spectroscopic studies. These examples include:

  • Generalized Two-Dimensional Correlation Studies of Polymers and Liquid Crystals
  • Two-Dimensional Correlation Spectroscopy and Chemical Reactions
  • Protein Research by Two-Dimensional Correlation Spectroscopy
  • Applications of 2D Correlation Spectroscopy to Biological and Biomedical Sciences
  • Application of Hetero-spectral Correlation Analysis
  • Extension of Two-Dimensional Correlation Analysis to Other Field

Two-Dimensional Correlation Spectroscopy serves as an introductory text for newcomers to the field, as well as presents a survey of specific interest areas for the experienced practitioners.


  1. Introduction
  2. Principle of Two-dimensional Correlation Spectroscopy
  3. Practical Computation of Two-dimensional Correlation Spectra
  4. Generalized Two-dimensional Correlation Spectroscopy in Practice
  5. Further Expansion of Generalized Two-dimensional Correlation Spectroscopy – Sample–Sample Correlation and Hybrid Correlation
  6. Additional Developments in Two-dimensional Correlation Spectroscopy – Statistical Treatments, Global Phase Maps, and Chemometrics
  7. Other Types of Two-dimensional Spectroscopy
  8. Dynamic Two-dimensional Correlation Spectroscopy Based on Periodic Perturbations
  9. Applications of Two-dimensional Correlation Spectroscopy to Basic Molecules
  10. Generalized Two-dimensional Correlation Studies of Polymers and Liquid Crystals
  11. Two-dimensional Correlation Spectroscopy and Chemical Reactions.
  12. Protein Research by Two-dimensional Correlation Spectroscopy.
  13. Applications of Two-dimensional Correlation Spectroscopy to Biological and Biomedical Sciences.
  14. Application of Heterospectral Correlation Analysis.
  15. Extension of Two-dimensional Correlation Analysis to Other Fields.


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Two-Dimensional Correlation Spectroscopy:
Applications in Vibrational and Optical Spectroscopy

by Isao Noda and Yukihiro Ozaki
295 pages • $204.00 + shipping
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