Obesity leads to a host of pathologies, including cardiovascular disease, insulin resistance, and metabolic syndrome.

Central to all of these pathologies is the concept that obesity produces chronic inflammation.

Featuring contributions from international experts in the fields of adiposity, inflammation, adipokines, and pharmaconutrition, Adipose Tissue and Inflammation focuses on the effects of obesity on systemic inflammation.

The text addresses:

• the epidemiology of obesity-induced inflammation
• the adipokine mediators that link adipose tissue to inflammation
• the influence of hormones on adipose inflammation
• the roles of nutrients, lifestyles, and pharmacotherapy in reducing inflammation and obesity

Contents

1. White Adipose Tissue Distribution in the Human Body
2. Epidemiology: Obesity and Inflammation
3. Role of Adipose Tissue in Inflammation
4. Inflammatory and Anti-Inflammatory Mediators Secreted by Adipose Tissue
5. Metabolic Pathways Regulating the Synthesis of Cytokines
6. Hormones/Mediators Influencing Adipose Inflammation: Role of Insulin
7. Hormones/Mediators Influencing Adipose Inflammation: Role of Growth Hormone
8. Hormones/Mediators Influencing Adipose Inflammation: Role of Glucocorticoids
9. Hormones/Mediators Influencing Adipose Inflammation: Role of Prostaglandins
10. Hormones/Mediators Influencing Adipose Inflammation: Role of Leptin and Other Adipose Tissue Hormones
11. Role of Diet in Modulating Adipose Tissue Inflammation: Polyunsaturated Fatty Acids; n-6; n-3 and Conjugated Linoleic Acid
12. Role of Diet in Modulating Adipose Tissue Inflammation: Phytosterols and Phytoestrogens
13. Role of Diet in Modulating Adipose Tissue Inflammation: Antioxidants and Polyphenols
14. Role of Exercise and Weight Loss in Reducing Inflammation
15. Role of Drugs in Reducing Inflammation

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