Adverse Drug Reactions is an essential and practical guide to the reactions that affect particular organ systems.
Contents
Introduction
- Epidemiology
- Classification and Mechanisms
- Susceptibility
- Detection and Diagnosis
- Healthcare Professionals and Adverse Drug Reactions
Side Effects and Patients
- Desire for Information About Side Effects
- General Perceptions
- Side Effects and Compliance
- Mandatory Patient Information Leaflets
- Format of Side-Effect Data for Patients
- Key Effects to Consider When Presenting Side-Effect Data
- Patient Reporting of ADRs
- The Way Forward
Pharmacogenetics and Adverse Drug Reactions
- Adverse Drug Reactions
- Drug Action
- Genetics Revisited
- Genetic Polymorphism and Drug Transporters
- Genetically Determined Pharmacodynamic Variations
- Human Leukocyte Antigens and Adverse Drug Reactions
- Utility of Pharmacogenetics in the Clinical Setting
Adverse Drug Reactions in Pregnancy
- Prescribing in Pregnancy
- Drugs Used to Treat Selected Cardiovascular System Disorders
- Drugs Used to Treat Epilepsy
- Mental Health Disorders
- Drugs Used in Endocrine Disorders
- Drugs Used to Treat Infections
- Miscellaneous Agents
Drug-Induced Skin Reactions
- Classification and Mechanism
- Diagnosis
- Management Points
- Exanthematous (Erythematous) Reactions
- Fixed Drug Eruption
- Urticaria and Angio-Oedema
- Acne
- Psoriasis and Psoriasiform Eruptions
- Purpura
- Vasculitis
- Erythema Multiforme, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
- Blistering Drug Eruptions
- Photosensitivity
- Lichenoid Drug Eruptions
- Pigmentary Disorders
- Alopecia
- Hair Gain
- Nail Disorders
Gastrointestinal Disorders
- The Mouth
- The Oesophagus
- Nausea and Vomiting
- Stomach and Duodenum
- Small Intestine
- Colon
- Constipation
- Pancreatitis
Hepatic Disorders
- Classification and Mechanisms
- Signs and Symptoms of Liver Disorders
- Risk Factors
- Diagnosis of Drug-Induced Liver Damage
- Types of Drug-Induced Liver Disease
- Management of Patients with Drug-Induced Hepatic Disease
- Prevention of Drug-Induced Hepatic Damage
Renal Disorders
- Risk Factors
- Diagnosis of Drug-Induced Renal Dysfunction
- Acute Renal Failure
- Chronic Renal Failure
- Nephrogenec Diabetes Insipidus
- Haemolytic Uraemic Syndrome
- Osmotic Nephrosis
Endocrine and Metabolic Disorders
- Drugs Affecting Thyroid Function
- Medicines That May Interfere With Thyroid Function
- Drugs Affecting Adrenal Function
- Aldosterone Synthesis
- Drugs Affecting Gonadotrophin Release and Gonadal Function
- Hyperprolactinaemia
- Syndrome of Inappropriate Secretion of Antidiuretic Hormone
- Hyperglycaemia and Diabetes
- Hypoglycaemia
- Disorders of Fat Metabolism
Respiratory Disorders
- Nasal Congestion
- Airway Obstruction
- Parenchymal Lung Disorders
- Pulmonary Oedema
- Pulmonary Thromboembolism
Musculoskeletal Disorders
- Muscle Disorders
- Bone
- Joints
- Connective Tissue
Blood Disorders
- Aplastic Anaemia
- Agranulocytosis
- Thrombocytopenia
- Pure Red Cell Aplasia
- Haemolytic Anaemia
- Megaloblastic Anaemia
Mental Health Disorders
- Depression
- Psychosis
- Mania
- Behavioural Toxicity
- Cognitive Impairment
- Psychiatric Manifestations of Drug Withdrawal Reactions
- Use of SSRIs and Venlafaxine in Children and Adoloscents with Major Depressive Disorder
- Serotonin Syndrome and Neuroleptic Psychiatric Disturbances
Cardiovascular Effects
- Disorders of Cardiac Rhythm
- Disorders of Systemic Blood Pressure
- Congestive Heart Failure
- Myocardial Toxicity
- Pulmonary Hypertension
- Stroke and Heart Attack Risk
Neurological Disorders
- Headache
- Effects on the Neuromuscular Junction and Myasthenia Gravis
- Seizures
- Coma and Encephalopathy
- Neuropathies
- Guillain-Barré Syndrome
- Drug-Induced Movement Disorders
- Sudden Sleep Onset with Dopaminergic Drugs
Sexual Dysfunction and Infertility
- Infertility
- Sexual Dysfunction
Index
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