Advances in Neurology Volume 99 provides a summary review of all recently published and ongoing research initiatives related to Tourette Syndrome.
The latest research is presented in a clinical context, and controversial issues are fully discussed using an evidence-based approach.
These issues include the following:
- The prevalence of Tourette Syndrome
- The nature of the Tourette Syndrome phenotype
- The role of autoimmunity in the development of Tourette Syndrome
- The role of comorbidity in functional outcomes of Tourette Syndrome patients
- Approaches to identifying the Tourette Syndrome gene/genes
Contents
Clinical Phenomenology
- Phenomenology and Natural History of Tic Disorders
Co-Morbid Disorders
- Attention Deficit Hyperactivity Disorder: The Childhood Co-Morbidity That Most Influences the Disability Burden in Tourette Syndrome
- Obsessive-Compulsive Disorder in Tourette Syndrome
- Behavioral and Affective Disorders in Tourette Syndrome
- Tics Associated with Other Disorders
New Findings in Basic Neurosciences
- Preclinical Models Relevant to Tourette Syndrome
- Neurobiology of Basal Ganglia and Tourette Syndrome: Basal Ganglia Circuits and Thalamocortical Outputs
- Neurobiology of Basal Ganglia and Tourette Syndrome: Striatal and Dopamine Function
Neuroimaging and Neurophysiology
- Motor Cortex Inhibitory Function in Tourette Syndrome, Attention Deficit Disorder, and Obsessive Compulsive Disorder: Studies Using Transcranial Magnetic Stimulation
- Functional Neuroimaging of Tourette Syndrome: Advances and Future Directions
Genetics and Molecular Biology of TS
- A Genome-Wide Scan and Fine Mapping in Tourette Syndrome Families
- Web-Based Consensus Diagnosis for Genetics Studies of Gilles de la Tourette Syndrome
- Genes and Tourette Syndrome: Scientific, Ethical, and Social Implications
Immunology and TS
- Preclinical/Clinical Evidence of Central Nervous System Infectious Etiology in PANDAS
- PANDAS: Overview of the Hypothesis
- Autoimmunity and Pediatric Movement Disorders
- PANDAS: To Treat or Not to Treat?
Epidemiology and Defining the Phenotype
- Disruptive Behavior Problems in a Community Sample of Children with Tic Disorders
Advances in Treatment
- Treatment of Tics
- Attention Deficit Hyperactivity Disorder, Chronic Tic Disorder, and Methylphenidate
- Treatment of Co-Morbid Obsessive Compulsive Disorder, Mood, and Anxiety Disorders
- Treatment of Aggression in Tourette Syndrome
- Behavioral Treatments for Tic Suppression: Habit Reversal Training
- Behavior Therapy: Other Interventions for Tic Disorders
- Behavioral Neurosurgery
- Future and Alternative Therapies in Tourette Syndrome
Index