Allergy and Allergic Diseases is an outstanding reference source on all aspects of allergy and allergic diseases.

Covering every allergic condition, from the immunological and molecular basis of the allergic response to the future trends in allergic disease prevention, this new edition has been completely revised and updated to take account of new and recent developments, from both a scientific and clinical perspective.

The second edition is in two volumes, containing over 100 chapters and will deal with the immunologic basis of the allergic response and then with the cells and mediators responsible for allergic inflammation. Descriptions of the pharmacology and physiology of allergic diseases is given, and then each specific allergic disease and their management are addressed.

The new edition contains 14 principal sections, and an increased coverage of drug allergens and allergic hypersensitivity reaction to drugs and the field of genetics has been revised accordingly.

Allergy and Allergic Diseases includes a fully searchable CD-ROM including a database of 100 color images.

Contents

Volume 1: The Scientific Basis of Allergy

Part 1 Immunology of the Allergic Response

1. Allergy and Hypersensitivity: History and Concepts
2. Development of Allergy and Atopy
3. T Cells and Cytokines in Asthma and Allergic Inflammation
4. Regulatory T Cells and Other Tolerogenic Mechanisms in Allergy and Asthma
5. IgE and IgE Receptors
6. Immunoglobulin Gene Organization and Expression and Regulation of IgE
7. Environmental Factors in IgE Production
8. Antigen-presenting Dendritic Cells and Macrophages
9. Innate Immunity in Allergic Disease
10. Signal Transduction in Allergic and Inflammatory Cells

Part 2 Inflammatory Cells and Mediators

11. Mast Cells: Biological Properties and Role in Health and Allergic Diseases
12. Eosinophils: Biological Properties and Role in Health and Disease
13. Neutrophils: Biological Properties and Role in Health and Allergic Diseases
14. Basophils: Biological Properties and Role in Allergic Diseases
15. Leukocyte Adhesion in Allergic Inflammation
16. Airway Epithelium
17. Airway Vascularity in Asthma
18. Fibroblasts and the Extracellular Matrix
19. Immune Complexes and Complement: Their Role in Host Defense and in Disease
20. Bradykinin Pathways and Allergic Disease
21. Chemokines
22. Neurotrophins
23. Neuropeptides
24. Late-phase Allergic Reactions in Humans

Part 3 Pharmacology

25. Antihistamines
26. Lipid Mediators: Leukotrienes, Prostanoids, Lipoxins, and Platelet-activating Factor
27. Theophylline and Isoenzyme-selective Phosphodiesterase Inhibitors
28. Adrenergic Agonists and Antagonists
29. Cholinergic Antagonists
30. Antileukotriene Agents
31. Glucocorticosteroids
32. Immunomodulating Drugs

Part 4 Physiology

33. Physiologic Aspects of Asthma
34. Aerosol Delivery Systems
35. Bronchial Hyperresponsiveness
36. Exercise-induced Bronchoconstriction: Animal Models
37. Exercise-induced Bronchoconstriction: Human Models
38. Sensory and Autonomic Nervous System in Asthma and Rhinitis
39. Mucus and Mucociliary Clearance in Asthma and Allergic Rhinitis
40. Biology of Vascular Permeability
41. Airway Smooth Muscle

Part 5 Allergens

42. Biochemistry of Allergens and Recombinant Allergens
43. Host Responses to Allergens
44. Allergen Extracts and Standardization
45. Grass, Tree, and Weed Pollen
46. Fungi as Allergens
47. Dust Mites and Asthma
48. Animal Allergens
49. Airborne Allergens and Irritants in the Workplace
50. Allergens from Stinging Insects: Ants, Bees, and Vespids
51. Cockroach Allergens, Environmental Exposure, and Asthma
52. Food Allergens
53. Latex Allergy

Part 6 Animal Models of Asthma

54. Primate Models of Allergic Asthma
55. Airway Remodeling in Small Animal Models
56. Are Animal Models of Asthma Useful?

Index

Volume 2: Allergic Diseases: Etiology, Diagnosis and Treatment

Part 7 Etiology and Pathology

57. Genetics of Asthma and Atopic Dermatitis
58. Epidemiology of Asthma, Atopy, and Atopic Disease
59. The Allergy March
60. Outdoor Air Pollution and Allergic Airway Disease
61. Indoor Air Pollution
62. Molecular Immunopathology of Allergic Disease

Part 8 Diagnosis of Allergic Disease

63. Principles and Practice of Diagnosis and Treatment of Allergic Disease
64. Skin Testing in Diagnosis and Management of Respiratory Allergic Diseases
65. Allergy Testing in the Laboratory
66. Measurement of Markers of Inflammation in Induced Sputum and Exhaled Air

Part 9 Allergic Rhinoconjunctivitis and Immunotherapy

67. Definition and Classification of Allergic Rhinitis and Upper Airways Diseases
68. Pathophysiology of Allergic Rhinitis
69. Management and Treatment of Allergic Rhinitis
70. Nasal Polyps and Rhinosinusitis
71. Ocular Allergy
72. Mechanisms in Allergen Injection Immunotherapy
73. Allergen Injection Immunotherapy: Indications and Practice
74. Sublingual Immunotherapy
75. Novel Approaches to Allergen Immunotherapy

Part 10 Asthma and its Treatment

76. Definition, Clinical Features, Investigations, and Differential Diagnosis of Asthma
77. Asthma in Infancy and Childhood
78. Pathogenesis of Asthma
79. Pathology of Asthma
80. Management of Chronic Asthma
81. Anti-IgE in Persistent Severe Allergic Asthma
82. Occupational Asthma
83. New Drugs for the Treatment of Allergy and Asthma

Part 11 Eosinophil-associated Disease and Hypersensitivity Pneumonitis

84. Allergic Bronchopulmonary Aspergillosis
85. Extrinsic Allergic Alveolitis/Hypersensitivity Pneumonitis
86. Pulmonary Eosinophilia
87. Hypereosinophilic Syndromes

Part 12 Allergy and the Skin

88. Atopic Dermatitis 89 Contact Dermatitis 90 Urticaria and Angioedema 91 Mastocytosis

Part 13 Anaphylaxis and Allergy to Food and Drugs

92. Anaphylaxis
93. Food Allergy and Eosinophilic Gastroenteropathies
94. Drug Hypersensitivity
95. Hypersensitivity to Aspirin and other NSAIDs
96. Insect Sting Allergy

Part 14 Prevention of Allergic Disease

97. Prevention of Allergic Disease
98. Prevalence of Atopic Disorders in a Developing World: Pitfalls and Opportunities

Index

click here to see books • videos • cd-roms of related interest