Allergy/Allergic Diseases Handbook
from C.H.I.P.S.

Allergy and Allergic Diseases
2-Volume Set
Second edition
edited by A. Barry Kay

Allergy and Allergic Diseases is an outstanding reference source on all aspects of allergy and allergic diseases.

Covering every allergic condition, from the immunological and molecular basis of the allergic response to the future trends in allergic disease prevention, this new edition has been completely revised and updated to take account of new and recent developments, from both a scientific and clinical perspective.

The second edition is in two volumes, containing over 100 chapters and will deal with the immunologic basis of the allergic response and then with the cells and mediators responsible for allergic inflammation. Descriptions of the pharmacology and physiology of allergic diseases is given, and then each specific allergic disease and their management are addressed.

The new edition contains 14 principal sections, and an increased coverage of drug allergens and allergic hypersensitivity reaction to drugs and the field of genetics has been revised accordingly.

Allergy and Allergic Diseases includes a fully searchable CD-ROM including a database of 100 color images.


Volume 1: The Scientific Basis of Allergy

Part 1 Immunology of the Allergic Response

  1. Allergy and Hypersensitivity: History and Concepts
  2. Development of Allergy and Atopy
  3. T Cells and Cytokines in Asthma and Allergic Inflammation
  4. Regulatory T Cells and Other Tolerogenic Mechanisms in Allergy and Asthma
  5. IgE and IgE Receptors
  6. Immunoglobulin Gene Organization and Expression and Regulation of IgE
  7. Environmental Factors in IgE Production
  8. Antigen-presenting Dendritic Cells and Macrophages
  9. Innate Immunity in Allergic Disease
  10. Signal Transduction in Allergic and Inflammatory Cells

Part 2 Inflammatory Cells and Mediators

  1. Mast Cells: Biological Properties and Role in Health and Allergic Diseases
  2. Eosinophils: Biological Properties and Role in Health and Disease
  3. Neutrophils: Biological Properties and Role in Health and Allergic Diseases
  4. Basophils: Biological Properties and Role in Allergic Diseases
  5. Leukocyte Adhesion in Allergic Inflammation
  6. Airway Epithelium
  7. Airway Vascularity in Asthma
  8. Fibroblasts and the Extracellular Matrix
  9. Immune Complexes and Complement: Their Role in Host Defense and in Disease
  10. Bradykinin Pathways and Allergic Disease
  11. Chemokines
  12. Neurotrophins
  13. Neuropeptides
  14. Late-phase Allergic Reactions in Humans

Part 3 Pharmacology

  1. Antihistamines
  2. Lipid Mediators: Leukotrienes, Prostanoids, Lipoxins, and Platelet-activating Factor
  3. Theophylline and Isoenzyme-selective Phosphodiesterase Inhibitors
  4. Adrenergic Agonists and Antagonists
  5. Cholinergic Antagonists
  6. Antileukotriene Agents
  7. Glucocorticosteroids
  8. Immunomodulating Drugs

Part 4 Physiology

  1. Physiologic Aspects of Asthma
  2. Aerosol Delivery Systems
  3. Bronchial Hyperresponsiveness
  4. Exercise-induced Bronchoconstriction: Animal Models
  5. Exercise-induced Bronchoconstriction: Human Models
  6. Sensory and Autonomic Nervous System in Asthma and Rhinitis
  7. Mucus and Mucociliary Clearance in Asthma and Allergic Rhinitis
  8. Biology of Vascular Permeability
  9. Airway Smooth Muscle

Part 5 Allergens

  1. Biochemistry of Allergens and Recombinant Allergens
  2. Host Responses to Allergens
  3. Allergen Extracts and Standardization
  4. Grass, Tree, and Weed Pollen
  5. Fungi as Allergens
  6. Dust Mites and Asthma
  7. Animal Allergens
  8. Airborne Allergens and Irritants in the Workplace
  9. Allergens from Stinging Insects: Ants, Bees, and Vespids
  10. Cockroach Allergens, Environmental Exposure, and Asthma
  11. Food Allergens
  12. Latex Allergy

Part 6 Animal Models of Asthma

  1. Primate Models of Allergic Asthma
  2. Airway Remodeling in Small Animal Models
  3. Are Animal Models of Asthma Useful?


Volume 2: Allergic Diseases: Etiology, Diagnosis and Treatment

Part 7 Etiology and Pathology

  1. Genetics of Asthma and Atopic Dermatitis
  2. Epidemiology of Asthma, Atopy, and Atopic Disease
  3. The Allergy March
  4. Outdoor Air Pollution and Allergic Airway Disease
  5. Indoor Air Pollution
  6. Molecular Immunopathology of Allergic Disease

Part 8 Diagnosis of Allergic Disease

  1. Principles and Practice of Diagnosis and Treatment of Allergic Disease
  2. Skin Testing in Diagnosis and Management of Respiratory Allergic Diseases
  3. Allergy Testing in the Laboratory
  4. Measurement of Markers of Inflammation in Induced Sputum and Exhaled Air

Part 9 Allergic Rhinoconjunctivitis and Immunotherapy

  1. Definition and Classification of Allergic Rhinitis and Upper Airways Diseases
  2. Pathophysiology of Allergic Rhinitis
  3. Management and Treatment of Allergic Rhinitis
  4. Nasal Polyps and Rhinosinusitis
  5. Ocular Allergy
  6. Mechanisms in Allergen Injection Immunotherapy
  7. Allergen Injection Immunotherapy: Indications and Practice
  8. Sublingual Immunotherapy
  9. Novel Approaches to Allergen Immunotherapy

Part 10 Asthma and its Treatment

  1. Definition, Clinical Features, Investigations, and Differential Diagnosis of Asthma
  2. Asthma in Infancy and Childhood
  3. Pathogenesis of Asthma
  4. Pathology of Asthma
  5. Management of Chronic Asthma
  6. Anti-IgE in Persistent Severe Allergic Asthma
  7. Occupational Asthma
  8. New Drugs for the Treatment of Allergy and Asthma

Part 11 Eosinophil-associated Disease and Hypersensitivity Pneumonitis

  1. Allergic Bronchopulmonary Aspergillosis
  2. Extrinsic Allergic Alveolitis/Hypersensitivity Pneumonitis
  3. Pulmonary Eosinophilia
  4. Hypereosinophilic Syndromes

Part 12 Allergy and the Skin

  1. Atopic Dermatitis 89 Contact Dermatitis 90 Urticaria and Angioedema 91 Mastocytosis

Part 13 Anaphylaxis and Allergy to Food and Drugs

  1. Anaphylaxis
  2. Food Allergy and Eosinophilic Gastroenteropathies
  3. Drug Hypersensitivity
  4. Hypersensitivity to Aspirin and other NSAIDs
  5. Insect Sting Allergy

Part 14 Prevention of Allergic Disease

  1. Prevention of Allergic Disease
  2. Prevalence of Atopic Disorders in a Developing World: Pitfalls and Opportunities


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Allergy and Allergic Diseases
2-Volume Set
Second edition edited by A. Barry Kay

2008 • 2,184 pages • $445.00 + shipping
Texas residents please add 6.75 % sales tax

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