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Pharmaceutical Book from C.H.I.P.S.

Allosteric Receptor Modulation in Drug Targeting
edited by Norman G. Bowery

Allosteric Receptor Modulation in Drug Targeting covers the principles of allosterism in reference to drug action and progresses to a detailed examination of individual ionotropic and G-protein coupled receptor systems.

Features:

  • Provides a thorough analysis of the impact of allosterism on drug action
  • Includes a section on mathematical models of allosteric receptor interactions for predicting dose-response behavior
  • Vontains detailed examples of allosterism in relation to a variety of receptor systems
  • Describes comparative features on the given examples of receptors

Contents

Basic Principles

  • Allosteric Modulation of Receptor Function
  • Characteristics of Allosterism in Drug Action
  • Predicting Dose-Response Curve Behavior: Mathematical Models of Allosteric Ligand-Receptor Interactions

Ionotropic Receptors

  • Allosteric Modulation of GABAA Receptors: A Pharmacology of Sleep, Anxiety and Memory
  • Allosteric Interactions at the NMDA Receptor Channel Complex
  • 5-HT3 Receptors
  • Nicotinic Receptors

G-Protein Coupled Receptors

  • Allosteric Modulation of G protein-coupled Receptors
  • Adenosine Receptor
  • Allosteric Modulators of Group III Metabotropic Glutamate Receptors as Novel Therapeutics
  • Allosteric Modulation of Gamma-Aminobutyric Acid B (GABAB) Receptors
  • Allosteric Interactions at GABAB and Related G-Protein-Coupled Receptors
  • Muscarinic Receptors: Targeting Allosteric Modulation by the Development and Application of the Radiolabeled Allosteric Agent [3H]dimethyl-W84
  • Alpha 2 Adrenoceptors: Physiology, Pharmacology and Allosteric Modulation

Index

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Allosteric Receptor Modulation in Drug Targeting
edited by Norman G. Bowery
2006 376 pages $228.95 + shipping
Texas residents please add 6.75 % sales tax

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