Amyotrophic Lateral Sclerosis examines all aspects of ALS from pathology to patient care and provides the reader with a ready reference to help with the difficulties encountered in patient diagnosis and treatment.

Features:

• Stands as the only comprehensive textbook available on the topic
• Is completely reorganized and revised new edition
• Contains a full color tip-in plate section

Contents

1. The Spectrum of Motor Neuron Disorders
2. Epidemiology of Amyotrophic Lateral Sclerosis
3. Neuroimaging in ALS
4. Motor Unit Number Estimation in ALS
5. The corticomotoneuronal system in ALS
6. Conventional Neurophysiology in ALS
7. The Neuropsychology of ALS
8. Familial motor neuron diseases other than ALS
9. ALS Genetics with Mendelian Inheritance
10. Modifying Genes in ALS
11. From Genetic Defects to Molecular Pathogenesis of Memory and Movement Disorders
12. Transgenic Mouse and Mutagenesis Models
13. Apoptotic Cell Death Pathways in Amyotrophic Lateral Sclerosis: A Review
14. Aging and Neurodegeneration
15. Neurotrophic Factors
16. Axonal transport and ALS
17. Mitochondrial dysfunction and energy metabolism in ALS
18. Therapeutic Trials in ALS: Past, Present and Future
19. Palliative care and quality of life with ALS

Index

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