Angiogenesis presents the latest advances in basic science and reviews the status of the clinical applications of angiogenic growth factors and inhibitors.

Features:

• Provides the most current and timely review of the angiogenesis field
• Presents a unique combination of basic science and clinical trials research
• Describes the molecular mechanisms of angiogenesis and anti-angiogenesis
• Includes coverage of results from clinical trials of an anti-angiogenic antibody

Contents

1. Vascular Endothelial Growth Factor: Pathophysiology and Clinical Implications
2. Signal Transduction of VEGF Receptors toward Angiogenesis
3. Growth Factors and Lymphangiogenesis
4. Notch and Vascular Development
5. Neural Guidance Molecules in Vascular Development
6. Neuropilins, Receptors for the VEGF and Semaphorin Families, Link Angiogenesis and Axon Guidance
7. Non-Angiogenic Functions of VEGF
8. Contribution of Pro-Angiogenic Hematopoietic Cells to Vascularization of Tumor and Ischemic Tissue
9. Selected Antiangiogenic Drugs as Potentially Effective Universal Chemosensitizers
10. Using an Anti-VEGF Monoclonal Antibody to Treat Cancer
11. Ocular Neovascularization
12. Targeting VEGF for Neovascular Age-Related Macular Degeneration and Macular Edema
13. Therapeutic Angiogenesis for Cardiovascular Disease

Index

click here to see books related interest