Providing must-have knowledge for the pharmaceutical industry and process chemists in industry, this ready reference offers solutions for saving time and money and supplying -- in a sustainable way -- valuable products.

Application-oriented and well structured, each chapter presents successful strategies for the latest modern drugs, showing how to provide very fast bulk quantities of drug candidates.

Throughout, the text illustrates how all the key factors are interwoven and dependent on one another in creating optimized methods for optimal products.

Contents

1. Efavirenz®, a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate
2. CCR5 Receptor Antagonist
3. 5a-Reductase Inhibitors – The Finasteride Story
4. Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist
5. SERM: Selective Estrogen Receptor Modulator
6. HIV Integrase Inhibitor: Raltegravir
7. Cyclopentane-Based NK1 Receptor Antagonist
8. Glucokinase Activator
9. CB1R Inverse Agonist – Taranabant

Index

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