Bioactive Heterocycles VII: Flavonoids and Anthocyanins in Plants and Latest Bioactive Heterocycles II presents:

• comprehensive and up-to-date reviews on selected topics concerning mainly the usefulness for human health of flavonoids and related compounds
• Sophora flavonoids and their functions in Sophora species (Leguminosae)
• the relationship of biological activity with the diverse structures of heterocycles by quantumchemical calculation
• advances in bioactive mesoionic heterocycles
• the spectroscopic properties and application of bioactive phenothiazines including also benzo[a]phenothiazines

Contents

1. Anthocyanins as Functional Food Colors presents the structures of flavonoids and anthocyanins and their functions, especially protective activity against age-related diseases suchashypertension, diabetes, heartdefectsandothers.

2. Flavonoids in Sophora Species presents the relationships of diverse Sophora flavonoids with their functions in Sophora species of Leguminosae,which abundantly exist in the natural kingdom.

3. Quantitative Structure-Cytotoxicity Relationship of Bioactive Heterocycles by the Semi-empirical Molecular Orbital Method with the Concept of Absolute Hardness presents the relationship between the cytotoxicity (defined as 50% cytotoxic concentration) of heterocycles such as phenoxazine, 5-trifluoromethyloxazoles, O-heterocycles such as 3- formylchromone and coumarins, and vitamin K2 derivatives against some tumor cell lines and 15 chemical descriptors.

4. The Chemistry of Bioactive Mesoionic Heterocycles presents the latest developments in the biologically interesting mesoionic compounds, such as sydnones, sydnonimines, 1,2,3,4-oxatriazolium-5-aminates, and 1,3,4- thiadiazolium-2-aminides, mainly since 2000.

5. Bioactive Phenothiazines and Benzo[a]phenothiazines: Spectroscopic Studies, Biological and Biomedical Properties and Applications presents recent advances in the spectroscopic, photophysical, photochemical, and analytical studies of bioactive phenothiazines andbenzophenothiazines, including also their biological and biomedical properties, as well as recent results from the authors of this review chapter.

Index

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