Biomonitoring Methods provides detailed, ready-to-use protocols for human biomonitoring methods, which were developed to monitor concentrations of occupational toxicants, yet can be equally used for environmental monitoring.

Biomonitoring Methods includes:

• data on precision
• accuracy
• detection limit
• calibration procedures
• potential sources of systematic errors

Contents

Working Group Analytical Chemistry of the Commission of the Deutsche Forschungsgemeinschaft for the Investigation of Health Hazards of Chemical Compounds in the Work Area

• Organization – Objectives and operational procedure – Development, examination, release and quality of the analytical methods – Publications of the working group – Withdrawal of methods

Terms and Symbols Used

• Terminology – symbols

General Remarks

• The use of gas chromatography-mass spectrometry in biological monitoring

Analytical Methods

• Alkoxycarboxylic acids in urine as metabolites of glycol ethers with a primary alcohol group
• Aminodinitrotoluenes in urine as metabolites of trinitrotoluene
• Bromide in plasma and serum
• 3,4-Dichlorocatechol and 4,5-dichlorocatechol in urine
• Furan-2-carboxylic acid and other carboxylic acids (phenylglyoxylic acid, mandelic acid, t,t-muconic acid, benzoic acid, hydroxybenzoic acid, hippuric acid, methylhippuric acid, 2,4-dichlorobenzoic acid, 3-methyl-4-nitro-benzoic acid, TTCA)
• Manganese in blood
• Methylmercury in blood
• Perfluorooctanoic acid in plasma
• Perfluorooctane sulphonic acid and perfluorobutane sulphonic acid in plasma and urine
• Titanium in blood and urine
• 3,5,6-Trichloro-2-pyridinol (TCPyr) in urine

Members and Guests of the Working Subgroup Analyses of Hazardous Substances in Biological Materials of the Commission of the Deutsche Forschungsgemeinschaft for the Investigation of Health Hazards of Chemical Compounds in the Work Area

Index

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