Biological and Pharmaceutical Nanomaterials presents knowledge on important natural biological compounds that form nanomaterials or that may be used to purposefully create them.

Features:

• Brings together the many articles published in specialized journals which often remain unseen by members of the other, related disciplines
• Covers DNA, plant and animal proteins, and lipoplexes
• Focuses on materials and technologies needed for the continued growth of medicine, healthcare, pharmaceuticals and human wellness applications

Contents

Self-assembled DNA Nanotubes

• DNA Nanotubes Self-assembled from DX Tiles
• 3DAE-E DX Tile Nanotubes
• DAE-O DX Tile Nanotubes
• TX Tile Nanotubes
• 4x4 Tile Nanotubes
• 6HB Tile Nanotubes

Nucleic Acid Nanoparticles

• The Chemical and Physical Properties of Therapeutic DNA
• Preparation of Nucleic Acid Nanoparticles: Synthesis and Characterization
• DNA Functionalization for Cell Recognition and Internalization
• DNA Nanoparticles: Sophistication for Cell Recognition and Internalization

Lipoplexes

• DNA Lipoplexes
• ODN Lipoplexes
• siRNA Lipoplexes

DNA–Chitosan Nanoparticles for Gene Therapy: Current Knowledge and Future Trends

• Chitosan as a Carrier for Gene Therapy
• Modified Chitosans: Strategies to Improve the Transfection Efficacy
• Methods of Preparation of Chitosan Nanoparticles
• DNA Loading into Nano- and Microparticles of Chitosan
• DNA Release and Release Kinetics
• Preclinical Evidence of Chitosan–DNA Complex Efficacy
• Potential Clinical Applications of Chitosan–DNA in Gene Therapy

Plant Protein-based Nanoparticles

• Description of Plant Proteins
• Preparation of Protein Nanoparticles
• Drug Encapsulation in Plant Protein Nanoparticles
• Preparation of Ligand–Gliadin Nanoparticle Conjugates
• Bioadhesive Properties of Gliadin Nanoparticles

Peptide Nanoparticles

• Starting Materials for the Preparation of Nanoparticles
• Preparation Methods
• Basic Characterization Techniques for Peptide Nanoparticles
• Drug Targeting with Nanoparticles
• Applications as Drug Carriers and for Diagnostic Purposes
• Immunological Reactions with Protein-based Microspheres

Albumin Nanoparticles

• Serum Albumin
• Preparation of Albumin Nanoparticles
• Biodistribution of Albumin Nanoparticles
• Pharmaceutical Applications

Nanoscale Patterning of S-Layer Proteins as a Natural Self-assembly System

• General Properties of S-Layers.
• Nanoscale Patterning of S-Layer Proteins
• Spatial Control over S-Layer Reassembly
• S-Layers as Templates for the Formation of Regularly Arranged Nanoparticles

Methods of Preparation of Drug Nanoparticles

• Structures of Drug Nanoparticles
• Thermodynamic Approaches
• Mechanical Approaches
• SCF Approaches
• Electrostatic Approaches

Production of Biofunctionalized Solid Lipid Nanoparticles for Site-specific Drug Delivery

• Concept of Differential Adsorption
• Production of SLN
• Functionalization by Surface Modification

Biocompatible Nanoparticulate Systems for Tumor Diagnosis and Therapy

• Nanoscale Particulate Systems and their Building Blocks/Components
• Biodegradable Nanoparticles
• Biodegradable Optical Nanoparticles
• Optical Imaging and PDT
• PLGA-based Nanoparticulate Delivery System for ICG

Nanoparticles for Crossing Biological Membranes

• Cell Membranes
• Problems of Drugs Crossing through Biological Membranes
• Nanoparticulate Drug Delivery
• Nanoparticulate Delivery to the BBB
• Oral Nanoparticulate Delivery

Index

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