Pharmaceutical Book from C.H.I.P.S.

Biological and Pharmaceutical Nanomaterials
edited by Challa S. S. R. Kumar

Biological and Pharmaceutical Nanomaterials presents knowledge on important natural biological compounds that form nanomaterials or that may be used to purposefully create them.


  • Brings together the many articles published in specialized journals which often remain unseen by members of the other, related disciplines
  • Covers DNA, plant and animal proteins, and lipoplexes
  • Focuses on materials and technologies needed for the continued growth of medicine, healthcare, pharmaceuticals and human wellness applications


Self-assembled DNA Nanotubes

  • DNA Nanotubes Self-assembled from DX Tiles
  • 3DAE-E DX Tile Nanotubes
  • DAE-O DX Tile Nanotubes
  • TX Tile Nanotubes
  • 4x4 Tile Nanotubes
  • 6HB Tile Nanotubes

Nucleic Acid Nanoparticles

  • The Chemical and Physical Properties of Therapeutic DNA
  • Preparation of Nucleic Acid Nanoparticles: Synthesis and Characterization
  • DNA Functionalization for Cell Recognition and Internalization
  • DNA Nanoparticles: Sophistication for Cell Recognition and Internalization


  • DNA Lipoplexes
  • ODN Lipoplexes
  • siRNA Lipoplexes

DNA–Chitosan Nanoparticles for Gene Therapy: Current Knowledge and Future Trends

  • Chitosan as a Carrier for Gene Therapy
  • Modified Chitosans: Strategies to Improve the Transfection Efficacy
  • Methods of Preparation of Chitosan Nanoparticles
  • DNA Loading into Nano- and Microparticles of Chitosan
  • DNA Release and Release Kinetics
  • Preclinical Evidence of Chitosan–DNA Complex Efficacy
  • Potential Clinical Applications of Chitosan–DNA in Gene Therapy

Plant Protein-based Nanoparticles

  • Description of Plant Proteins
  • Preparation of Protein Nanoparticles
  • Drug Encapsulation in Plant Protein Nanoparticles
  • Preparation of Ligand–Gliadin Nanoparticle Conjugates
  • Bioadhesive Properties of Gliadin Nanoparticles

Peptide Nanoparticles

  • Starting Materials for the Preparation of Nanoparticles
  • Preparation Methods
  • Basic Characterization Techniques for Peptide Nanoparticles
  • Drug Targeting with Nanoparticles
  • Applications as Drug Carriers and for Diagnostic Purposes
  • Immunological Reactions with Protein-based Microspheres

Albumin Nanoparticles

  • Serum Albumin
  • Preparation of Albumin Nanoparticles
  • Biodistribution of Albumin Nanoparticles
  • Pharmaceutical Applications

Nanoscale Patterning of S-Layer Proteins as a Natural Self-assembly System

  • General Properties of S-Layers.
  • Nanoscale Patterning of S-Layer Proteins
  • Spatial Control over S-Layer Reassembly
  • S-Layers as Templates for the Formation of Regularly Arranged Nanoparticles

Methods of Preparation of Drug Nanoparticles

  • Structures of Drug Nanoparticles
  • Thermodynamic Approaches
  • Mechanical Approaches
  • SCF Approaches
  • Electrostatic Approaches

Production of Biofunctionalized Solid Lipid Nanoparticles for Site-specific Drug Delivery

  • Concept of Differential Adsorption
  • Production of SLN
  • Functionalization by Surface Modification

Biocompatible Nanoparticulate Systems for Tumor Diagnosis and Therapy

  • Nanoscale Particulate Systems and their Building Blocks/Components
  • Biodegradable Nanoparticles
  • Biodegradable Optical Nanoparticles
  • Optical Imaging and PDT
  • PLGA-based Nanoparticulate Delivery System for ICG

Nanoparticles for Crossing Biological Membranes

  • Cell Membranes
  • Problems of Drugs Crossing through Biological Membranes
  • Nanoparticulate Drug Delivery
  • Nanoparticulate Delivery to the BBB
  • Oral Nanoparticulate Delivery


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Biological and Pharmaceutical Nanomaterials
edited by Challa S. S. R. Kumar
2006 • 428 pages • $199.00 + shipping
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