As with many other spectroscopic techniques, Raman and infrared spectroscopy have made great progress due to recent developments in optics, detectors, nanotechnology, and computer science.

Biomedical Vibrational Spectroscopy focuses on methodologies that are most relevant to biodiagnostics.

Biomedical Vibrational Spectroscopy covers:

• Current spectroscopic applications suitable for routine use in cytology,histopathology, and clinical chemistry
• New spectroscopic directions providing increased analytical sensitivity or spatial resolution that make them suitable for in vivo and in situ applications such as resonant Raman scattering, CARS, SERS, and PTIR
• Study design and the analysis of vibrational spectral fingerprints from complex biological and clinical samples

Contents

1. Vibrational Spectroscopy in Microbiology and Medical Diagnostics
2. Biomedical Vibrational Spectroscopy - Technical Advances
3. Biomedical Applications of Infrared Microspectroscopy and Imaging by Various Means
4. Infrared Spectroscopy of Biofluids in Clinical Chemistry and Medical Diagnostics
5. Raman Spectroscopy of Biofluids
6. Vibrational Microspectroscopy of Cells and Tissues
7. Resonance Raman Microspectroscopy and Imaging of Hemoproteins in Single Leukocytes
8. Resonant Raman Scattering of Heme Molecules in Cells and in the Solid State
9. Coherent Anti-Stokes Raman Scattering (CARS) microscopy
10. Surface-Enhanced Raman Sensors for Metabolic Analytes
11. Surface-enhanced Raman Scattering for Investigations of Eukaryotic Cells
12. Combining Optical Coherence Tomography and Raman Spectroscopy for Investigating Dental and Other Mineralized Tissues
13. From Study Design to Data Analysis
14. Interpreting Several Types of Measurements in Bioscience
15. Classification of Spectral Data in Biomedical Spectroscopy and Imaging

Index

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