Burger's Medicinal Chemistry
and Drug Discovery
Sixth Edition 6 Volumes
Special Set Price $2,449.00 + shipping
Individual Volumes: $479.00 each + shipping
Burgers Medicinal Chemistry and Drug Discovery offers several new and unique features. For the first time, all of the volumes are structured entirely according to content and published simultaneously to provide broad coverage of medicinal chemistry and drug discovery for new or experienced medicinal chemists, biologists, pharmacologists and molecular biologists. This includes a current and global perspective of drug design, and drug development.
With expanded content from 69 chapters to over 100 chapters, this sixth edition includes more than 50% new material. Areas included are those at the foreground of life science including:
Proteomics Genomics Bioinformatics Combinatorial Chemistry High-Throughput Screening Blood Substitutes Allosteric Effectors as Potential Drugs COX Inhibitors Statins High-Throughput Pharmacology and more!
Volume 1: Drug Discovery
Contents
- History of Quantitative Structure Activity Relationships
- Recent Trends in QSAR
- Molecular Modeling in Drug Design
- Drug-Target Binding Forces: Advances in Force Field Approaches
- Combinatorial Library Design, Molecular Similarity and Diversity Applications
- Virtual Screening
- Docking and Scoring Functions/Virtual Screening
- Bioinformatics
- Chemical Information Computing Systems
- X-ray Crystallography
- NMR and Drug Discovery
- Mass Spectrometry and Drug Discovery
- Electron Cryomicroscopy of Biological Macromolecules
- Design of Peptidomimetics
- Analog Design
- Approaches to the Rational Design of Enzyme Inhibitors
- Chirality and Biological Activity
- Structural Concepts in the Prediction of the Toxicity of Therapeutical Agents
- Natural Products as Leads for New Pharmaceuticals
Index
1,125 pages $479.00 + shipping
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Volume 2: Discovery and Drug Development
Contents
- Combinatorial Chemistry and Multiple Parallel Synthesis
- High-Throughput Screening for Lead Discovery
- High-Throughput Pharmacology
- Application of Recombinant DNA Technology in Medicinal Chemistry and Drug Discovery
- Oligonucleotide Therapeutics
- Therapeutic Agents Acting on RNA
- Carbohydrate-Based Therapeutics
- Membrane Transport Proteins and Drug Transport
- Allosteric Proteins and Drug Discovery
- Receptor Targets in Drug Discovery and Development
- Nicotinic Acetylcholine Receptors
- Large-Scale Synthesis
- Principles of Drug Metabolism
- Metabolic Considerations in Prodrug Design
- Retrometabolism-Based Drug Design and Targeting
- Drug Discovery: The Role of Toxicology
- Drug Absorption, Distribution, and Elimination
- Physicochemical Characterization and Principles of Oral Dosage Form Selection
- The FDA and Regulatory Issues
- Intellectual Property in Drug Discovery and Biotechnology
Index
808 pages $479.00 + shipping
Volume 3: Cardiovascular Agents and Endocrine
Contents
- Cardiac Drugs
- Diuretic and Uricosuric Agents
- Myocardial Infarction Agents
- Endogenous Vasoactive Peptides
- Hematopoietic Agents
- Anticoagulants, Antithrombotics, and Hemostatics
- Antihyperlipedemic Agents
- Oxygen Delivery via Allosteric Effectors of Hemoglobin, Blood Substitutes, Plasma Expanders
- Inhibition of Sickle Hemoglobin Polymerization as a Basis For Therapeutic Approach to Sickle-Cell Anemia
- Iron Chelators
- Thyroid Hormones and Thyromimetics
- Fundamentals of Steroid Chemistry and Biochemistry
- Female Sex Hormones, Contraceptives and Fertility Drugs
- Male Sex Hormones, Analogs and Antagonists
- Anti-inflammatory Steroids
Index
912 pages $479.00 + shipping
Volume 4: Autocoids, Diagnostics, and Drugs from New Biology
Contents
- Insulin and Hypoglycemic Agents
- Peptide and Protein Hormones, Peptide Neurotransmitters, and Therapeutic Agents
- Inhibitors of Gastric Acid Secretion
- Chemokines and Cytokine Modulators
- COX-2 Inhibitors and Leukotriene Modulators
- Agents Acting on Prostanoid Receptors
- Retinoids
- Vitamins
- Life Style and Over-the-Counter Drugs
- Radiopaques
- Microarrays and Gene Expression Profiling Applied to Drug Research
- SNPs: Single Nucleotide Polymorphisms and Pharmacogenomics
- Plasmid DNA-Mediated Gene Therapy
702 pages $479.00 + shipping
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Volume 5: Chemotherapeutic Agents
Contents
- Molecular Biology of Cancer
- Synthetic DNA-Targeted Chemotherapeutic Agents and Related Tumor-Activated Prodrugs
- Antitumor Natural Products
- Radiosensitizers and Radioprotective Agents
- Synthetic Anti-angiogenic Agents
- Future Strategies in Immunotherapy
- Selective Toxicity
- Drug Resistance in Cancer Chemotherapy
- Antiviral Agents, DNA
- Antiviral Agents, RNA Viruses and Orthopoxviruses
- Rationale of Design of Anti-HIV Drugs
- Organ Transplant Drugs
- Synthetic Antibacterial Agents
- Lactam Antibiotics
- Tetracyclines, Aminolycoside, Macrolide, and Miscellaneous Antibiotics
- Antimycobacterial Agents
- Antifungal Agents
- Antimalarial Agents
- Antiprotozoal Agents
- Anthelmintics
Index
808 pages $479.00 + shipping
Volume 6: Nervous System Agents
Contents
- Andrenergics and Andrenergic-Blocking Agents
- Cholinergics
- Anticholinergic Drugs
- CNS Stimulants
- Sedatives-Hypnotics
- Anticonvulsants
- Narcotic Analgesics
- Antidepressants
- Antianxiety Agents
- Antipsychotic Agents
- Investigative Agents for use in Neurodegenerative Conditions
- Therapeutic and Diagnostic Agents for Parkinsons Disease
- Alzheimers Disease: Search for Therapeutics
- Cognition Enhancers
- Drugs to Treat Eating and Body Weight Disorders
Index
1,084 pages $479.00 + shipping
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