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Calcium Signaling
Second Edition
edited by James W. Putney

Calcium Signaling focuses on those processes that generate calcium signals to compile the first comprehensive exploration of calcium signaling research from a methodological standpoint.

Features:

  • Explores the molecular basis, as well as the complex aspects, of calcium signaling
  • Employs an easy-to-follow format in describing numerous research techniques, along with the pros and cons of each approach
  • Discusses the major intracellular and surface membrane calcium channel molecules and intracellular effectors in terms of their molecular nature and biophysical behavior
  • Introduces the application of high-throughput technology, and the use of genetically tractable organisms such as C. elegans, and yeast

Contents

  • Fluorescent Calcium Indicators Based on BAPTA
  • Fluorescent Indicators-Facts and Artifacts
  • Fluorescence Microplate-Based Techniques for the High-Throughput Assessment of Calcium Signaling: The Highs and Lows for Calcium Researchers
  • Genetically Encoded Fluorescent Calcium Indicator Proteins
  • Targeted Aequorins
  • Electrophysiological Recordings of Ca2o Currents
  • Molecular Biology of Ca2o Channels: Lessons from the TRP Superfamily
  • Genetic and Molecular Characterization of Ca2o and IP3 Signaling in the Nematode Caenorhabditis elegans
  • Calcium Signaling Networks in Yeast
  • Nuclear Patch Clamp Electrophysiology of Inositol Trisphosphate Receptor Ca2o Release Channels
  • Ryanodine Receptors
  • Methods in Cyclic ADP-Ribose and NAADP Research
  • Methods for Studying Calcium Pumps
  • Measuring Single Cell and Subcellular Ca2o Signals
  • Subcellular Compartmentalization of Calcium Signaling
  • Apoptosis
  • Calcium Entry Channels and Drug Discovery

Index

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Calcium Signaling
Second Edition
edited by James W. Putney

2005 536 pages $178.95 + shipping
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