by Siamon Gordon
Topics covered include:
- The epidemiological links between cancer and inflammation
- The parallels between inflammation and cancer
- The role of inflammation in cancer
- Inflammatory genes as risk factors for cancer initiation and progression
- Inflammation and cancer angiogenesis
- Preventative and therapeutic strategies
- Plus many more!
This book draws together contributions from an international group of scientists and clinicians from diverse disciplines, ranging from epidemiology to immunology, cell biology, molecular oncology, molecular medicine and pharmacology to debate these and related issues.
Contents
- Inflammation and cancer: an epidemiological perspective
- Chemokine-based pathogenetic mechanisms in cancer
General Discussion I
- Anti-TNF therapy of rheumatoid arthritis: what can we learn about chronic disease?
- How do chemokine/chemokine receptor activations affect tumorigenesis?
- Proinflammatory cytokines, immune response and tumour progression
General discussion II
- Lymphangiogenesis and tumour metastasis
- Infiltration of tumours by macrophages and dendritic cells: tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
- The influence of CD25+ cells on the generation of immunity to tumour cell-lines in mice
- Macrophages: modulators of breast cancer progression
- Chemokines: angiogenesis and metastases in lung cancer
- Macrophage infiltration and angiogenesis in human malignancy
- The role of inflammation for tumour growth and tumour suppression
- Cyclooxygenase 2: from inflammation to carcinogenesis
- The inflammatory cytokine network of epithelial cancer: therapeutic implications
- In vivo manipulation of DC migration and activation to elicit anti-tumour immunity
Final general discussion
Concluding remarks
Subject Index
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