Cardiovascular Genetics and Genomics for the Cardiologist helps cardiologists understand:

• how cardiovascular genetics may remodel the way cardiovascular medicine is practiced
• what material has immediate relevance to the practicing clinician
• how to incorporate genetics and genomics in your practice to ensure up-to-date patient care

Cardiovascular Genetics and Genomics for the Cardiologist discusses:

• cardiovascular single gene disorders
• cardiovascular polygenic disorders
• therapies and applications

Contents

1. The gene in the twenty-first century

Cardiovascular single gene disorders

2. Monogenic hypercholesterolemia
3. Hypertrophic cardiomyopathy
4. Dilated cardiomyopathy and other cardiomyopathies
5. The long QT syndrome

Cardiovascular polygenic disorders

6. Atherosclerosis
7. Heart failure
8. The implications of genes on the pathogenesis, diagnosis and therapeutics of hypertension

Therapies and applications

9. Gene therapy for cardiovascular disease: inserting new genes, regulating the expression of native genes, and correcting genetic defects
10. Stem cell therapy for cardiovascular disease
11. Pharmacogenetics and personalized medicine
12. The potential of blood-based gene profiling for disease assessment

Index

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