edited by Giorgio Minotti
Cardiotoxicity of Non-Cardiovascular Drugs international experts describe the molecular mechanisms and clinical read-outs of cardiac events induced by a broad variety of noncardiovascular drugs. Particular emphasis is been paid to the preclinical screening of drug cardiotoxicity.
Cardiotoxicity of Non-Cardiovascular Drugs is an essential guide to this important area of drug development. It will find a place on the bookshelves of researchers, regulators and students in medicinal chemistry, drug development, pharmacology, pharmacy and cardiovascular disease.
Topics covered include:
Contents
Chapter 1: Mitochondrial Dysfunction In Cell Injury and Cardiotoxicity
Chapter 2: Cardiovascular Liabilities of Drugs: Regulatory Aspects
Chapter 3: Cellular Mechanisms, Molecular Targets, and Structure-Function Relationships In Drug-Induced Arrhythmias: The Case Of Antihistamines, Psychoactive Drugs, and Antimicrobial Agents
Chapter 4: Cardiovascular Toxicity of Antitumor Drugs: Dimensions of the Problem in Children
Chapter 5: Cardiovascular Toxicity of Antitumor Drugs: Dimension of the Problem in Adult Settings
Chapter 6: Diagnostic Aspects of Cardiovascular Toxicity of Antitumor Drugs
Chapter 7: Cardiovascular Toxicity of Antitumor Drugs: Translating Molecular Mechanisms into Clinical Facts
Chapter 8: NSAID Action and the Foundations for Cardiovascular Toxicity
Chapter 9: Cardiovascular toxicities of NSAIDS: Epidemiologic aspects
Chaper 10: Cardiovascular Toxicities of Life-Saving Drugs: Antiviral Therapy
Index
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