Cardiovascular Regeneration and Stem Cell Therapy is the definitive reference on two of the most exciting areas of cardiovascular research – myocardial regeneration and stem cell therapy – for the treatment of disease.

Cardiovascular Regeneration and Stem Cell Therapy covers:

• The biology of stem cells
• The actions of stem cells from the bone marrow, the heart, and embryos on the normal restorative and repair functions of the heart and blood vessels
• How stem cells could contribute to myocardial recovery in the face of injury and aging
• How adjuvant therapy with growth factors might enhance stem cell activity in regeneration and repair
• Clinical applications and clinical experiences

Contents

Stem Cell Biology

1. Homing of Stem Cells and Tissue Injury
2. Adult Stem Cell Plasticity: Lineage Potential on a Continuum
3. Embryonic Stem Cells and Cardiogenesis
4. Mesenchymal Stem Cell-Derived Cardiomyogenic Cells
5. Bone Marrow Cells and Vascular Growth
6. Progenitor Cells and Vascular Repair

Cardiac Progenitor Cells in the Adult Heart

7. Cardiac Side Population Cells: Phenotype and Functional Significance
8. Phenotype and Function of c-kit Positive-Derived Amplifying Myocytes
9. Cardiac Stem Cells and their Niches
10. Activation of the Local Regenerative System of the Heart

Progenitor Cells and the Diseased Heart

11. Embryonic Stem Cells and Myocardial Regeneration
12. Bone Marrow-Derived Cells in Myocardial Repair and Regeneration
13. Endothelial Progenitor Cells And The Infarcted Heart
14. Cytokines and Heart Remodeling
15. IGF-1, Muscle Progenitors and Heart Failure

Cardiac Progenitor Cells and Heart Failure

16. Cardiac Stem Cells and the Diabetic Cardiomyopathy
17. Stem Cells and Cardiac Aging
18. Bioengineered Scaffolds: Myocytes, Endothelial Cells and Cardiac Repair
19. Gene Therapy and Cellular Therapy in Cardiac Repair
20. Cardiac Stem Cells and the Failing Heart
21. Myocardial Infarction: Risks and Hope

Index

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