Cell Adhesion provides an overview of the main topics of current cell adhesion research including structural analyses of cell adhesion molecules and studies to their functional role in vitro and in vivo.

Cell Adhesion focuses on the four major families of cell-adhesion receptors, i.e. the cadherins, the integrins, the Ig-superfamily and the selectin-based adhesion system which are discussed in detail by numerous experts in the field.

Contents

Cadherins

• Cadherin Adhesion: Mechanisms and Molecular Interactions
• Structural Aspects of Adherens Junctions and Desmosomes
• Cadherins in Development
• Cadherins in Cancer
• In Vivo Functions of Catenins
• The Molecular Composition and Function of Desmosomes

Integrins and Extracellular Matrix

• Regulation of Signal Transduction by Integrins
• Integrins and Extracellular Matrix in Animal Models
• Hemidesmosomes: Molecular Organization and Their Importance for Cell Adhesion and Disease

Immunoglobulin Superfamily

• CEA-Related CAMs
• Roles of Nectins in Cell Adhesion, Signaling and Polarization
• Ig Superfamily Cell Adhesion Molecules in the Brain

Physiology and Pathology of Cell Adhesion

• Adhesion Mechanisms of Endothelial Cells
• Pharmacology of Platelet Adhesion and Aggregation

Index

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