Chemistry of Fungi
by James R. Hanson

Chemistry of Fungi is an introduction to the chemistry of fungal metabolites. It illustrates within the context of fungal metabolites:

• the historical progression from chemical to spectroscopic methods of structure elucidation
• the development in biosynthetic studies from establishing sequences and mechanisms to chemical enzymology and genetics
• the increasing understanding of the biological roles of natural products

The book begins with a historical introduction followed by a description of the general chemical features which contribute to the growth of fungi. There are many thousands of fungal metabolites whose structures are known and the book does not aim to list them all as there are databases to fulfill this role. Instead, it describes some of the more important metabolites classified according to their biosynthetic origin.

Biosynthesis provides a unifying feature underlying the diverse structures of fungal metabolites and the chapters covering this area begin with a general outline of the relevant biosynthetic pathway before presenting a detailed description of particular metabolites. Investigations into these biosyntheses have utilized many subtle isotopic labelling experiments and compounds that are fungal pigments and those which are distinctive metabolites of the more conspicuous

Basidiomycetes are treated separately. The use of fungi as reagents forms the subject of the final chapter.

Contents

1. Fungi and the development of microbiological chemistry
2. The chemistry of growing fungi
3. Fungal metabolites derived from amino acids
4. Polyketides from fungi
5. Terpenoid fungal metabolites
6. Fungal metabolites derived from the citric acid cycle
7. Pigments and odours of fungi
8. The chemistry of some fungal diseases of plants
9. Mycotoxins
10. Fungi as reagents

Index

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