Chemoprevention of Cancer and DNA Damage by Dietary Factors provides comprehensive coverage of all important aspects of chemoprevention of cancer and DNA-damage by dietary factors.

Special emphasis is given to:

• different molecular mechanisms of cancer prevention by dietary factors
• a variety of experimental approaches to study its preventive functions in vitro and in vivo
• the description of molecular mechanisms of defined nutritional ingredients

Contents

General Principles

• Molecular Mechanisms of Cancer Formation
• Consequences of DNA Damage
• The Role of Nutrition in the Etiology of Human Cancer
• Mechanisms of Antimutagenesis and Anticarcinogenesis (Overview)
• Induction of DNA Damage and Cancer by Food Components
• Interaction of Dietary Factors with Drug Metabolising Enzymes
• Regulation of Drug Metabolising and Antioxidant Enzymes
• Interaction of Dietary Factors with Cell Signalling and Cell Division
• Hormones and Cancer
• DNA Methylation
• Prevention of Angiogenesis and Metastasis
• Role of Oxidants and Antioxidants

Experimental Models and Methods Used in Chemoprevention Studies

• Experiments Concerning the Prevention of DNA damage
• Preneoplastic Foci Models and Long Term Carcinogenicity Studies with Rodents
• Methods Used to Study Alterations of Cell Signalling and Proliferation
• Measurement of Drug Metabolising Enzymes
• Detection of Dietary Antioxidants
• Genomics and Proteomics
• Design of Epidemiological Studies

Selected Chemopreventive Dietary Factors and Components

• Carotenoids and Vitamin A
• Vitamins D, C, E
• Folate and Vitamins B6 and B12
• Phytosterins
• Saponins
• Glucosinolates and Cruciferous Vegetables
• Selected Flavonoids
• Selected Phenolic Compounds
• Sulfides in Allium Vegetables
• Chlorphylls
• Dietary Fibers
• Non Starch Polysaccharides and their Degradation Products
• Fatty acids
• Coffee and its Constituents
• Teas
• Green Tea and its Constituents
• Chung
• Other teas
• Protective Components of Alcoholic Beverages
• Wine
• Beer
• Selected Spices and their ingredients
• Protease Inhibitors
• Phytoestrogens
• Lignans in Cereals
• Isoflavones in Soy
• Lactobacilli and Fermented Foods
• Micronutrients

Index

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ORDER NOW Chemoprevention of Cancer and DNA Damage by Dietary Factors edited by Siegfried Knasmuller 2009 • 838 pages • $215.00+ shipping Texas residents please add 6.75 % sales tax